ArticleEuropean heart journal2021
Long-term outcomes after myocardial infarction in middle-aged and older patients with congenital heart disease-a nationwide study.
Article in European heart journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 42 citations in OpenAlex.
- Outcomes after a first acute myocardial infarction in patients with or without congenital heart disease.European heart journal · 2026Article
- Long-Term Coronary Artery Complications Following the Arterial Switch Operation for Transposition of the Great Arteries-A Scoping Review.World journal for pediatric & congenital heart surgery · 2025Article
- The Unique Challenge of Coronary Artery Disease in Adult Patients with Congenital Heart Disease.Journal of clinical medicine · 2024Review
- Morbidity Burden in Patients With Ebstein Anomaly: The Natural History.Journal of the American Heart Association · 2024Article
- Atherosclerotic Risk Factor Prevalence in Adults With Congenital Heart Disease: A Meta-Analysis.JACC. Advances · 2024Article
- Contemporary Management of the Failing Fontan.Journal of clinical medicine · 2024Review
- Prediction of Vasoactive-Inotropic Score on Prolonged Mechanical Ventilation in Adult Congenital Heart Disease Patients After Surgical Treatment Combined with Coronary Artery Bypass Grafting.Brazilian journal of cardiovascular surgery · 2024Article
- Acquired Cardiovascular Diseases in Patients with Pulmonary Hypertension Due to Congenital Heart Disease: A Case Report.Medicina (Kaunas, Lithuania) · 2024Article
- CHD-CXR: a de-identified publicly available dataset of chest x-ray for congenital heart disease.Frontiers in cardiovascular medicine · 2024Article
- Prognosis of Chronic Kidney Disease and Metabolic Syndrome in Adults With Congenital Heart Disease.Journal of Korean medical science · 2023Article
- Coronary artery disease in adults with congenital heart disease.International journal of cardiology. Congenital heart disease · 2023Review
- Ventricular arrhythmia in congenital heart diseases with a systemic right ventricle.International journal of cardiology. Congenital heart disease · 2023Review
- Lifetime risk of comorbidity in patients with simple congenital heart disease: a Danish nationwide study.European heart journal · 2023Article
- Healthcare consumption in congenital heart disease: A temporal life-course perspective following pediatric cases to adulthood.International journal of cardiology. Congenital heart disease · 2023Article
- Fractures in patients with and without congenital heart disease - A nationwide register-based cohort study.International journal of cardiology. Congenital heart disease · 2022Article
- Major Adverse Cardiovascular Events in Korean Congenital Heart Disease Patients: A Nationwide Age- and Sex-Matched Case-Control Study.Yonsei medical journal · 2022Article
- Interventions in Adults With Repaired Coarctation of the Aorta.Journal of the American Heart Association · 2022Article
- Risk of cancer in young and older patients with congenital heart disease and the excess risk of cancer by syndromes, organ transplantation and cardiac surgery: Swedish health registry study (1930-2017).The Lancet regional health. Europe · 2022Article
- A novelExperimental and therapeutic medicine · 2022Article
- Born to Age: When Adult Congenital Heart Disease Converges With Geroscience.JACC. Advances · 2022Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsWe aimed to describe the risk of myocardial infarction (MI) in middle-aged and older patients with congenital heart disease (ACHD) and to evaluate the long-term outcomes after index MI in patients with ACHD compared with controls. METHODS AND
resultsA search of the Swedish National Patient Register identified 17 189 patients with ACHD (52.2% male) and 180 131 age- and sex-matched controls randomly selected from the general population who were born from 1930 to 1970 and were alive at 40 years of age; all followed up until December 2017 (mean follow-up 23.2 ± 11.0 years). Patients with ACHD had a 1.6-fold higher risk of MI compared with controls [hazard ratio (HR) 1.6, 95% confidence interval (CI) 1.5-1.7, P < 0.001] and the cumulative incidence of MI by 65 years of age was 7.4% in patients with ACHD vs. 4.4% in controls. Patients with ACHD had a 1.4-fold increased risk of experiencing a composite event after the index MI compared with controls (HR 1.4, 95% CI 1.3-1.6, P < 0.001), driven largely by the occurrence of new-onset heart failure in 42.2% (n = 537) of patients with ACHD vs. 29.5% (n = 2526) of controls.
conclusionPatients with ACHD had an increased risk of developing MI and of recurrent MI, new-onset heart failure, or death after the index MI, compared with controls, mainly because of a higher incidence of newly diagnosed heart failure in patients with ACHD. Recognizing and managing the modifiable cardiovascular risk factors should be of importance to reduce morbidity and mortality in patients with ACHD.
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