ArticleCommunity dentistry and oral epidemiology2021
Caries experience among children born after a complicated pregnancy.
Article in Community dentistry and oral epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.
- Maternal smoking during pregnancy and early childhood dental caries in children: a systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Oral health status and early childhood caries in preterm and full-term children: a cross-sectional study.BMC oral health · 2026Article
- Article
- Oral and craniofacial research in the Generation R study: an executive summary.Clinical oral investigations · 2023Article
- The association of maternal smoking and other sociobehavioral factors with dental caries in toddlers: A cross-sectional study.Frontiers in pediatrics · 2023Article
- Caries experience among children born after a complicated pregnancy.Community dentistry and oral epidemiology · 2021Article
- [The dentobiome and the minimum intervention in dentistry].Revista cientifica odontologica (Universidad Cientifica del Sur)Review
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Authors and funding
7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectivesBehavioural and lifestyle factors, as oral hygiene and diet, are well-established risk factors in the pathogenesis of dental caries, though displaying large differences in susceptibility across individuals. Since enamel formation already starts in utero, pregnancy course and outcome may eventually play a role in enamel strength and caries susceptibility. Therefore, we studied the association between history of pregnancy complications and the caries experience in their six-year-old children. The pregnancy complications included small for gestational age (SGA), spontaneous preterm birth (sPTB), gestational hypertension (GH), pre-eclampsia (PE), individually, and a combination of those, designated as placental syndrome.
methodsThis study was embedded in Generation R, a prospective longitudinal Dutch multiethnic pregnancy cohort study. Information about pregnancy complications was obtained from questionnaires completed by midwives and obstetricians with cross-validation in medical records. These included SGA, sPTB, GH and PE. Caries experience was assessed with the decayed, missing and filled teeth (dmft) index at a mean age of six years. The association between dental caries experience and a history of pregnancy complications was studied by using hurdle negative binomial (HNB) models.
resultsWe were able to assess the dmft index in 5323 six-year-old children (mean age 6.2 years, SD 0.5). We did not find an association between the different pregnancy complications and dental caries experience in childhood, whether for SGA, sPTB, GH, PE, or for the combined outcome placental syndrome (HNB estimates: OR 1.02, 95%CI 0.87 - 1.19; RR 0.90, 95%CI 0.78 - 1.04). Further adjustment of the models with different confounders did not alter the outcome.
conclusionsAlthough it is expected that prenatal stress can be a risk factor for caries development later in life, our findings do not support this hypothesis. Therefore, we believe disparities in caries experience between children are probably not explained by early life events during a critical intrauterine period of development.
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