SynthesisMedical microbiology and immunology2021
Early changes in laboratory parameters are predictors of mortality and ICU admission in patients with COVID-19: a systematic review and meta-analysis.
Synthesis in Medical microbiology and immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The prognostic value of absolute lymphocyte count and neutrophil-to-lymphocyte ratio for patients with metastatic breast cancer: a systematic review and meta-analysis.Frontiers in oncology · 2024Pooled it
- Efficacy of tocilizumab in the treatment of COVID-19: An umbrella review.Reviews in medical virology · 2022Pooled it
- Lower Serum Magnesium Is Associated with Mortality in Severe COVID-19: A Secondary Analysis of a Randomized Trial.Biological trace element research · 2025Trial
- Do certain blood groups increase COVID-19 severity and mortality?Global epidemiology · 2025Article
- Article
- Serial measurements of lymphocytes, D-dimer, LDH, and CRP do not improve the ability to predict COVID-19 adverse outcomes.The Journal of international medical research · 2023Article
- Machine Learning Successfully Detects Patients with COVID-19 Prior to PCR Results and Predicts Their Survival Based on Standard Laboratory Parameters in an Observational Study.Infectious diseases and therapy · 2023Article
- Establishment of sex-specific predictive models for critical illness in Chinese people with the Omicron variant.Frontiers in microbiology · 2023Article
- Baseline and early changes in laboratory parameters predict disease severity and fatal outcomes in COVID-19 patients.Frontiers in public health · 2023Article
- Associated Biochemical and Hematological Markers in COVID-19 Severity Prediction.Advances in medicine · 2023Article
- Article
- Clinical progress in MSC-based therapies for the management of severe COVID-19.Cytokine & growth factor reviews · 2022Review
- An algorithm to predict the need for invasive mechanical ventilation in hospitalized COVID-19 patients: the experience in Sao Paulo.Acute and critical care · 2022Article
- Analysis of Mortality in Unvaccinated Patients with COVID-19 and Cardiovascular Risk.Journal of clinical medicine · 2022Article
- Predicting Abnormalities in Laboratory Values of Patients in the Intensive Care Unit Using Different Deep Learning Models: Comparative Study.JMIR medical informatics · 2022Article
- Comprehensive Cytokine Profiling of Patients with COVID-19 Receiving Tocilizumab Therapy.International journal of molecular sciences · 2022Article
- Significance of hemogram-derived ratios for predicting in-hospital mortality in COVID-19: A multicenter study.Health science reports · 2022Article
- SARS-CoV-2 Spike Protein Binding of Glycated Serum Albumin-Its Potential Role in the Pathogenesis of the COVID-19 Clinical Syndromes and Bias towards Individuals with Pre-Diabetes/Type 2 Diabetes and Metabolic Diseases.International journal of molecular sciences · 2022Article
- Hematological changes associated with COVID-19 infection.Journal of clinical laboratory analysis · 2022Review
- Clinical Characteristics and Predictors of Mortality in Elderly Patients Hospitalized with COVID-19 in Bangladesh: A Multicenter, Retrospective Study.Interdisciplinary perspectives on infectious diseases · 2022Article
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
Despite the growing knowledge of the clinicopathological features of COVID-19, the correlation between early changes in the laboratory parameters and the clinical outcomes of patients is not entirely understood. In this study, we aimed to assess the prognostic value of early laboratory parameters in COVID-19. We conducted a systematic review and meta-analysis based on the available literature in five databases. The last search was on July 26, 2020, with key terms related to COVID-19. Eligible studies contained original data of at least ten infected patients and reported on baseline laboratory parameters of patients. We calculated weighted mean differences (WMDs) for continuous outcomes and odds ratios (ORs) with 95% confidence intervals. 93 and 78 studies were included in quantitative and qualitative syntheses, respectively. Higher baseline total white blood cell count (WBC), C-reactive protein (CRP), lactate-dehydrogenase (LDH), creatine kinase (CK), D-dimer and lower absolute lymphocyte count (ALC) (WMD
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