Evidence map›Paper›PMID 33219285›Full record

Observational studyScientific reports2020

A simple score derived from bone marrow immunophenotyping is important for prognostic evaluation in myelodysplastic syndromes.

J R Vido-Marques, S C Reis-Alves, S T O Saad, K Metze, I Lorand-Metze

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

J R Vido-MarquesDepartment of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, Brazil.
S C Reis-AlvesHematology and Hemotherapy Center, University of Campinas, Carlos Chagas Street, 480, Campinas, São Paulo, 13083-878, Brazil.
S T O SaadDepartment of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, Brazil.
K MetzeDepartment of Pathology, Faculty of Medical Sciences, University of Campinas, Campinas, Brazil.
I Lorand-MetzeDepartment of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, Brazil. ilmetze@unicamp.br.
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunophenotyping of bone marrow (BM) precursors has been used as an ancillary diagnostic tool in myelodysplastic syndromes (MDS), but there is no general agreement about which variables are the most relevant for prognosis. We developed a parsimonious prognostic model based on BM cell populations well-defined by phenotype. We analyzed 95 consecutive patients with primary MDS diagnosed at our Institution between 2005 and 2012 where BM immunophenotyping had been performed at diagnosis. Median follow-up: 42 months (4-199). Median age: 67 years (33-79). According to IPSS-R, 71 cases were low or intermediate risk. Flow variables significant in the univariate Cox analysis: "%monocytes/TNCs", "% CD16

Indexed as

Models, StatisticalAdultAgedAntigens, CD34Bone MarrowBone Marrow CellsCase-Control StudiesCell SeparationFeasibility StudiesFemaleFlow CytometryFollow-Up StudiesGPI-Linked ProteinsHumansImmunophenotypingKaplan-Meier EstimateAntigens, CD34FCGR3B protein, humanGPI-Linked ProteinsReceptors, IgG

Identifiers

PMID33219285
PMCPMC7679401
OpenAlexW3101656339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.