ArticleScientific reports2020
Field evaporation and atom probe tomography of pure water tips.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 41 citations in OpenAlex.
- Clinical-functional dissociation in bilateral vestibulopathy: determinants of disability beyond peripheral vestibular loss.Journal of neurology · 2026Article
- Thermomechanics of Picoliter Liquids Encapsulated in Metal Microarchitectures.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Mechanisms of ionization and of chemical reactions in charged microdroplets.Chemical science · 2025Review
- Scalable substrate development for aqueous sample preparation for atom probe tomography.Journal of microscopy · 2025Article
- Nanopore ion sources deliver individual ions of amino acids and peptides directly into high vacuum.Nature communications · 2024Article
- Nanoscale analysis of frozen honey by atom probe tomography.Scientific reports · 2022Article
- 3D sub-nanometer analysis of glucose in an aqueous solution by cryo-atom probe tomography.Scientific reports · 2021Article
- Atom probe tomography.Nature reviews. Methods primers · 2021Article
- Hydrogen and deuterium charging of lifted-out specimens for atom probe tomography.Open research Europe · 2021Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Measuring biological samples by atom probe tomography (APT) in their natural environment, i.e. aqueous solution, would take this analytical method, which is currently well established for metals, semi-conductive materials and non-metals, to a new level. It would give information about the 3D chemical structure of biological systems, which could enable unprecedented insights into biological systems and processes, such as virus protein interactions. For this future aim, we present as a first essential step the APT analysis of pure water (Milli-Q) which is the main component of biological systems. After Cryo-preparation, nanometric water tips are field evaporated with assistance by short laser pulses. The obtained data sets of several tens of millions of atoms reveal a complex evaporation behavior. Understanding the field evaporation process of water is fundamental for the measurement of more complex biological systems. For the identification of the individual signals in the mass spectrum, DFT calculations were performed to prove the stability of the detected molecules.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.