ArticleScientific reports2020
Robust alternative to the righting reflex to assess arousal in rodents.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 45 citations in OpenAlex.
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- A probabilistic model of behavioural emergence from general anaesthesia in mice.British journal of anaesthesia · 2025Article
- Emergence from general anaesthesia: stochastic or deterministic?British journal of anaesthesia · 2025Article
- Parafacial GABAergic neurone ablation induces behavioural resistance to volatile anaesthetic-induced hypnosis without reducing sleep.British journal of anaesthesia · 2025Article
- Cortical signatures linked to behavior quantitatively track arousal levels.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Connectome harmonic decomposition tracks the presence of disconnected consciousness during ketamine-induced unresponsiveness.British journal of anaesthesia · 2025Article
- Mild TBI Changes Brain and Plasma Neurosteroid Levels in Mice.Neurotrauma reports · 2025Article
- Neurobehavioral Disorders and Pathological Changes in the Brain of Mice Are Caused by Chronic Toxocara canis Larval Invasion with Low to Moderate Inoculum.Acta parasitologica · 2024Article
- Hormonal basis of sex differences in anesthetic sensitivity.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- On growth and form of animal behavior.Frontiers in integrative neuroscience · 2024Article
- Recombinant Slit2 suppresses neuroinflammation and Cdc42-mediated brain infiltration of peripheral immune cells via Robo1-srGAP1 pathway in a rat model of germinal matrix hemorrhage.Journal of neuroinflammation · 2023Article
- Oral Probiotic Expressing Human Ethanol Dehydrogenase Attenuates Damage Caused by Acute Alcohol Consumption in Mice.Microbiology spectrum · 2023Article
- A clinical experience-based Chinese herbal formula improves ethanol-induced drunken behavior and hepatic steatohepatitis in mice models.Chinese medicine · 2023Article
- Article
- Historical and Modern Evidence for the Role of Reward Circuitry in Emergence.Anesthesiology · 2022Review
- Capacity for consciousness under ketamine anaesthesia is selectively associated with activity in posteromedial cortex in rats.Neuroscience of consciousness · 2022Article
- Brain areas modulation in consciousness during sevoflurane anesthesia.Frontiers in integrative neuroscience · 2022Review
- Evolution and function of neurocognitive systems in non-human animals.Scientific reports · 2021Article
- Ontogenetic Oxycodone Exposure Affects Early Life Communicative Behaviors, Sensorimotor Reflexes, and Weight Trajectory in Mice.Frontiers in behavioral neuroscience · 2021Article
- Return of the Righting Reflex Does Not Portend Recovery of Cognitive Function in Anesthetized Rats.Frontiers in systems neuroscience · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The righting reflex (RR) is frequently used to assess level of arousal and applied to animal models of a range of neurological disorders. RR produces a binary result that, when positive, is used to infer restoration of consciousness, often without further behavioral corroboration. We find that RR is an unreliable metric for arousal/recovery of consciousness. Instead, cortical activity and motor behavior that accompany RR are a non-binary, superior criterion that accurately calibrates and establishes level of arousal in rodents.
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