Evidence map›Paper›PMID 33219115›Full record

Trial reportBritish journal of sports medicine2021

Effectiveness of progressive tendon-loading exercise therapy in patients with patellar tendinopathy: a randomised clinical trial.

Stephan J Breda, Edwin H G Oei, Johannes Zwerver, Edwin Visser, Erwin Waarsing, Gabriel P Krestin, Robert-Jan de Vos

4 registry-linked trialsOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in British journal of sports medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 54 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 11 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05659134 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Comparison of Alfredson Eccentric and Silbernagel Concentric-eccentric Therapeutical Protocol in Competitive Athletes With Chronic Achilles Tendinopathy

TypeinterventionalSponsorCharles University, Czech RepublicRan2022 to 2024Enrolled40ConditionsAchilles Tendinopathy, Tendon Injuries, Tendon Thickening, Pain, ChronicArmsAlfredson protocol, Silbernagel protocol
NCT06705881 narecruitingnot on this mapstarted 2024, after this paper: background citation

Efficacy of the Extracorporeal Shock Wave Therapy in Athletes With Patellar Tendinopathy

TypeinterventionalSponsorAhi Evran University Education and Research HospitalRan2024 to 2025Enrolled32ConditionsPatellar Tendinopathy, Patellar Tendon PainArmsEccentric exercise program (EEP), ESWT (Extracorporeal Shock Wave Therapy)
NCT06729437 narecruitingnot on this mapstarted 2024, after this paper: background citation

Effectiveness of Transcranial Direct Current Stimulation on Functionality and Pain in Individuals With Patellar Tendinopathy: Randomized Clinical Trial

TypeinterventionalSponsorUniversity of ValenciaRan2024 to 2027Enrolled42ConditionsPatellar TendinopathyArmstDCS + Therapeutic eccentric exercise, Sham tDCS + Therapeutic eccentric exercise
NCT07460492 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Therapeutic Plyometric-Based Strength-Endurance Exercise Program for Breast Cancer Patients and Survivors to Improve Quality of Life and Physical and Mental Function

TypeinterventionalSponsorUniversity of VigoRan2026 to 2027Enrolled51ConditionsNeoplams, Patients, Cancer SurvivorsArmsPlyometric Strength-Endurance Training, Conventional Strength Training
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 11 syntheses or guidelines pooled it, 130 citations in OpenAlex.

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  5. Exercise for patellar tendinopathy.The Cochrane database of systematic reviews · 2025
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  18. Association Between TJournal of magnetic resonance imaging : JMRI · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stephan J BredaDepartment of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, Zuid-Holland, The Netherlands s.breda@erasmusmc.nl.ORCID http://orcid.org/0000-0002-4612-9825
Edwin H G OeiDepartment of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, Zuid-Holland, The Netherlands.
Johannes ZwerverCentre for Human Movement Sciences, University Medical Centre Groningen, Groningen, The Netherlands.
Edwin VisserDepartment of Physical Therapy, Sportgeneeskunde Rotterdam, Rotterdam, Zuid-Holland, The Netherlands.
Erwin WaarsingDepartment of Orthopaedics and Sports Medicine, Erasmus MC, Rotterdam, Zuid-Holland, The Netherlands.
Gabriel P KrestinDepartment of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, Zuid-Holland, The Netherlands.
Robert-Jan de VosDepartment of Orthopaedics and Sports Medicine, Erasmus MC, Rotterdam, Zuid-Holland, The Netherlands.ORCID http://orcid.org/0000-0003-0372-0188
Erasmus MC · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the effectiveness of progressive tendon-loading exercises (PTLE) with eccentric exercise therapy (EET) in patients with patellar tendinopathy (PT).

methodsIn a stratified, investigator-blinded, block-randomised trial, 76 patients with clinically diagnosed and ultrasound-confirmed PT were randomly assigned in a 1:1 ratio to receive either PTLE or EET. The primary end point was clinical outcome after 24 weeks following an intention-to-treat analysis, as assessed with the validated Victorian Institute of Sports Assessment for patellar tendons (VISA-P) questionnaire measuring pain, function and ability to play sports. Secondary outcomes included the return to sports rate, subjective patient satisfaction and exercise adherence.

resultsPatients were randomised between January 2017 and July 2019. The intention-to-treat population (mean age, 24 years, SD 4); 58 (76%) male) consisted of patients with mostly chronic PT (median symptom duration 2 years). Most patients (82%) underwent prior treatment for PT but failed to recover fully. 38 patients were randomised to the PTLE group and 38 patients to the EET group. The improvement in VISA-P score was significantly better for PTLE than for EET after 24 weeks (28 vs 18 points, adjusted mean between-group difference, 9 (95% CI 1 to 16); p=0.023). There was a trend towards a higher return to sports rate in the PTLE group (43% vs 27%, p=0.13). No significant between-group difference was found for subjective patient satisfaction (81% vs 83%, p=0.54) and exercise adherence between the PTLE group and EET group after 24 weeks (40% vs 49%, p=0.33).

conclusionsIn patients with PT, PTLE resulted in a significantly better clinical outcome after 24 weeks than EET. PTLE are superior to EET and are therefore recommended as initial conservative treatment for PT.

Indexed as

PatellaAdultExercise TherapyFemaleHumansIntention to Treat AnalysisMaleNetherlandsPain MeasurementPatient CompliancePatient SatisfactionReturn to SportSingle-Blind MethodTendinopathyTreatment OutcomeUltrasonographyexercise rehabilitationoveruse injuryrandomised controlled trialsports rehabilitation programstendinopathy

Identifiers

PMID33219115
PMCPMC8070614
OpenAlexW3098426061

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.