Evidence map›Paper›PMID 33218686›Full record

ArticleBiochemical and biophysical research communications2021

Cu/Zn Superoxide Dismutase (Sod1) regulates the canonical Wnt signaling pathway.

Bindu Chandrasekharan, Claudia Montllor-Albalate, Alyson E Colin, Joshua L Andersen, Young C Jang, Amit R Reddi

Open access · greenAbstract read
In one paragraph

Article in Biochemical and biophysical research communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Copper, cuproptosis, and cancer: biology concepts of a novel cell death.Apoptosis : an international journal on programmed cell death · 2026
    Review
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  6. Genome-Scale Screening ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Sod1 integrates oxygen availability to redox regulate NADPH production and the thiol redoxome.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bindu ChandrasekharanSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Claudia Montllor-AlbalateSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Alyson E ColinSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Joshua L AndersenDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, UT, 84602, USA.
Young C JangSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA; Parker Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Amit R ReddiSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, 30332, USA; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA; Parker Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA. Electronic address: amit.reddi@chemistry.gatech.edu.
Georgia Institute of Technology · USBrigham Young University · US

Funding

The Role of Cu/Zn Superoxide Dismutase (SOD1) in Redox SignalingR01GM118744 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI REDDI, AMIT RAM · 2016 to 2020
$1.6M
The regulation and targeting of cell survival pathways in cancerR15CA202618 · NCI · BRIGHAM YOUNG UNIVERSITY · PI ANDERSEN, JOSHUA LYON · 2016 to 2019
$864k
NCI NIH HHS R15 CA202618NIGMS NIH HHS R01 GM118744
6 · The paper itself

Abstract

Cu/Zn Superoxide Dismutase (Sod1) catalyzes the disproportionation of cytotoxic superoxide radicals (O

Indexed as

Casein Kinase ICell ProliferationGene Expression RegulationHEK293 CellsHumansRNA InterferenceSuperoxide Dismutase-1Wnt Signaling PathwayCasein Kinase ISOD1 protein, humanSuperoxide Dismutase-1CancerCu/Zn superoxide dismutaseHydrogen peroxideReactive oxygen speciesRedox signalingSuperoxideWnt signaling

Identifiers

PMID33218686
PMCPMC7785591
OpenAlexW3105714413

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.