Evidence map›Paper›PMID 33218363›Full record

ArticleGenome medicine2020

Transparency, trust, and community welfare: towards a precision public health ethics framework for the genomics era.

Eric T Juengst, Annelies Van Rie

Open access · goldAbstract read
In one paragraph

Article in Genome medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Eric T JuengstCenter for Bioethics, School of Medicine, University of North Carolina at Chapel Hill, 333 MacNider Hall, Chapel Hill, NC, 27599-7240, USA. ejuengst@med.unc.edu.
Annelies Van RieFamily Medicine and Population Health, Faculty of Medicine, University of Antwerp, Campus Drie Eiken R232, Universiteitsplein 1, 2610, Wilrijk, Belgium.
University of Antwerp · BEUniversity of North Carolina at Chapel Hill · US

Funding

Fonds voor Wetenschappelijk onderzoek (BE) G0F8316N and T001018N.
6 · The paper itself

Abstract

Infectious disease control is experiencing a paradigm shift, as pathogen sequencing technologies and digital applications are increasingly implemented for control of diseases such as tuberculosis, Ebola, and COVID-19. A new ethical framework should be a critical part of this emerging paradigm to ensure that the benefit of precision public health interventions based on advances in genomics research is not outweighed by the risks they pose to individuals, families, and vulnerable segments of the population. We suggest that the ethical framework guiding practice in this domain combines standard precepts from public health ethics with emerging ethics principles from precision medicine.

Indexed as

PandemicsSARS-CoV-2Bioethical IssuesCOVID-19GenomicsHumansPrecision MedicinePublic HealthEthicsGenomic epidemiologyPathogen sequencingPrecision public health

Identifiers

PMID33218363
PMCPMC7677909
OpenAlexW3106119067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.