Evidence map›Paper›PMID 33218295›Full record

ArticleCell cycle (Georgetown, Tex.)2020

The long non-coding RNA TSLC8 inhibits colorectal cancer by stabilizing

Zhian Du, Tao Yu, Meina Sun, Yun Chu, Gang Liu

Open access · greenAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zhian DuDepartment of General Surgery, Tianjin Medical University General Hospital , Tianjin, 300052, China.
Tao YuDepartment of Oncology, Tianjin Medical University General Hospital , Tianjin, 300052, China.
Meina SunIntensive Care Unit, The First Affiliated Hospital of Jinzhou Medical University , Jinzhou, Liaoning, 121000, China.
Yun ChuIntensive Care Unit, The First Affiliated Hospital of Jinzhou Medical University , Jinzhou, Liaoning, 121000, China.
Gang LiuDepartment of General Surgery, Tianjin Medical University General Hospital , Tianjin, 300052, China.
Jinzhou Medical University · CNTianjin Medical University · CNTianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The colorectal cancer (CRC) dictates a common malignancy with high recurrence rate. Long non-coding RNAs (lncRNAs) belong to a class of regulatory factors involved in multiple cancers. In current work, we have uncovered a novel lncRNA named TSLC8. TSLC8 was dramatically downregulated in CRC samples and cell lines. Reintroduction of TSLC8 inhibited tumor sphere formation and viability in CRC cells.

Indexed as

AnimalsApoptosis Regulatory ProteinsColorectal NeoplasmsFemaleHCT116 CellsHumansMiceMice, NudeProto-Oncogene ProteinsRNA, Long NoncodingXenograft Model Antitumor AssaysApoptosis Regulatory ProteinsBBC3 protein, humanProto-Oncogene ProteinsRNA, Long Noncodingcolorectal cancerFOXO1TSLC8

Identifiers

PMID33218295
PMCPMC7751665
OpenAlexW3098248194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.