Evidence map›Paper›PMID 33218292›Full record

ArticleTissue engineering. Part A2021

Alginate-Based Bioinks for 3D Bioprinting and Fabrication of Anatomically Accurate Bone Grafts.

Tomas Gonzalez-Fernandez, Alejandro J Tenorio, Kevin T Campbell, Eduardo A Silva, J Kent Leach

Open access · greenAbstract read
In one paragraph

Article in Tissue engineering. Part A, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 118 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Three-dimensional-printed shape-memory composite scaffold for meniscus repair.The Journal of international medical research · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Temperature Controlled Cryoprinting.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. 3D Bioprinting in Limb Salvage Surgery.Journal of functional biomaterials · 2024
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tomas Gonzalez-FernandezDepartment of Biomedical Engineering, University of California, Davis, Davis, California, USA.
Alejandro J TenorioDepartment of Biomedical Engineering, University of California, Davis, Davis, California, USA.
Kevin T CampbellDepartment of Biomedical Engineering, University of California, Davis, Davis, California, USA.
Eduardo A SilvaDepartment of Biomedical Engineering, University of California, Davis, Davis, California, USA.
J Kent LeachDepartment of Biomedical Engineering, University of California, Davis, Davis, California, USA.
University of California, Davis · US

Funding

Dual peptide presentation from bioengineered carriers to potentiate stromal cell function and tissue repairR01DE025899 · NIDCR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEACH, J. KENT · 2017 to 2021
$2.5M
NIDCR NIH HHS R01 DE025899
6 · The paper itself

Abstract

To realize the promise of three-dimensional (3D) bioprinting, it is imperative to develop bioinks that possess the necessary biological and rheological characteristics for printing cell-laden tissue grafts. Alginate is widely used as a bioink because its rheological properties can be modified through precrosslinking or the addition of thickening agents to increase printing resolution. However, modification of alginate's physiochemical characteristics using common crosslinking agents can affect its cytocompatibility. Therefore, we evaluated the printability, physicochemical properties, and osteogenic potential of four common alginate bioinks: alginate-CaCl

Indexed as

BioprintingAlginatesOsteogenesisPrinting, Three-DimensionalTissue EngineeringTissue ScaffoldsAlginatesalginatebioinkbioprintingmesenchymal stromal cellosteogenesis

Identifiers

PMID33218292
PMCPMC8558068
OpenAlexW3103394214

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.