Evidence map›Paper›PMID 33218190›Full record

ArticleInternational journal of molecular sciences2020

E3 Ubiquitin Ligase APC/C

Kamini Kaushal, Sang Hyeon Woo, Apoorvi Tyagi, Dong Ha Kim, Bharathi Suresh, Kye-Seong Kim, Suresh Ramakrishna

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kamini KaushalGraduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Sang Hyeon WooGraduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Apoorvi TyagiGraduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Dong Ha KimGraduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Bharathi SureshGraduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Kye-Seong KimGraduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Suresh RamakrishnaGraduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.ORCID 0000-0002-4038-1085
Hanyang University · KR

Funding

National Research Foundation of Korea 2018M3A9H3022412
6 · The paper itself

Abstract

Fumarylacetoacetate hydrolase (FAH) is the last enzyme in the degradation pathway of the amino acids tyrosine and phenylalanine in mammals that catalyzes the hydrolysis of 4-fumarylacetoacetate into acetoacetate and fumarate. Mutations of the

Indexed as

UbiquitinationAnaphase-Promoting Complex-CyclosomeAntigens, CDCdh1 ProteinsGene Expression Regulation, NeoplasticHEK293 CellsHumansHydrolasesLiver NeoplasmsProteasome Endopeptidase ComplexProtein StabilityProteolysisUbiquitin-Protein LigasesAnaphase-Promoting Complex-CyclosomeAntigens, CDATP dependent 26S proteaseCdh1 ProteinsfumarylacetoacetaseFZR1 protein, humanHydrolasesProteasome Endopeptidase ComplexUbiquitin-Protein LigasesCRISPR/Cas9 knockoutin silico analysisliver cancerpost-translational modificationsubiquitin-proteasome system

Identifiers

PMID33218190
PMCPMC7699203
OpenAlexW3098549400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.