Evidence map›Paper›PMID 33218121›Full record

ArticleJournal of clinical medicine2020

Contemporary National Outcomes of Acute Myocardial Infarction-Cardiogenic Shock in Patients with Prior Chronic Kidney Disease and End-Stage Renal Disease.

Saraschandra Vallabhajosyula, Lina Ya'Qoub, Vinayak Kumar, Dhiran Verghese, Anna V Subramaniam, Sri Harsha Patlolla, Viral K Desai, Pranathi R Sundaragiri, Wisit Cheungpasitporn, Abhishek J Deshmukh and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Kidney Failure in Cardiogenic Shock.Circulation. Heart failure · 2026
    Review
  2. Article
  3. Management of non-Cardiac Organ Failure in cardiogenic shock.American heart journal plus : cardiology research and practice · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Saraschandra VallabhajosyulaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-1631-8238
Lina Ya'QoubDivision of Cardiovascular Medicine, Department of Medicine, Louisiana State University School of Medicine, Shreveport, LA 71115, USA.ORCID 0000-0002-4203-3228
Vinayak KumarDepartment of Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Dhiran VergheseDepartment of Medicine, Amita Health Saint Joseph Hospital, Chicago, IL 60657, USA.ORCID 0000-0003-1904-7397
Anna V SubramaniamDepartment of Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Sri Harsha PatlollaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0001-7952-0217
Viral K DesaiDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Pranathi R SundaragiriDivision of Hospital Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Wisit CheungpasitpornDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0001-9954-9711
Abhishek J DeshmukhDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Kianoush KashaniDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0003-2184-3683
Gregory W BarsnessDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Mayo Clinic in Arizona · USMayo Clinic · USAmita Health · USLouisiana State University in Shreveport · USUniversity of Louisville · US

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
NCATS NIH HHS UL1 TR000135
6 · The paper itself

Abstract

backgroundThere are limited data on acute myocardial infarction with cardiogenic shock (AMI-CS) stratified by chronic kidney disease (CKD) stages.

objectiveTo assess clinical outcomes in AMI-CS stratified by CKD stages.

methodsA retrospective cohort of AMI-CS during 2005-2016 from the National Inpatient Sample was categorized as no CKD, CKD stage-III (CKD-III), CKD stage-IV (CKD-IV) and end-stage renal disease (ESRD). CKD-I/II were excluded. Outcomes included in-hospital mortality, use of coronary angiography, percutaneous coronary intervention (PCI) and mechanical circulatory support (MCS). We also evaluated acute kidney injury (AKI) and acute hemodialysis in non-ESRD admissions.

resultsOf 372,412 AMI-CS admissions, CKD-III, CKD-IV and ESRD comprised 20,380 (5.5%), 7367 (2.0%) and 18,109 (4.9%), respectively. Admissions with CKD were, on average, older, of the White race, bearing Medicare insurance, of a lower socioeconomic stratum, with higher comorbidities, and higher rates of acute organ failure. Compared to the cohort without CKD, CKD-III, CKD-IV and ESRD had lower use of coronary angiography (72.7%, 67.1%, 56.9%, 61.1%), PCI (53.7%, 43.8%, 38.4%, 37.6%) and MCS (47.9%, 38.3%, 33.3%, 34.2%), respectively (all

conclusionsCKD/ESRD is associated with lower use of evidence-based therapies. ESRD was an independent predictor of higher in-hospital mortality in AMI-CS.

Indexed as

acute myocardial infarctioncardiogenic shockchronic kidney diseaseend-stage renal diseaseoutcomes research

Identifiers

PMID33218121
PMCPMC7698908
OpenAlexW3098049961

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.