Evidence map›Paper›PMID 33218095›Full record

ArticleMarine drugs2020

Exploiting Mannuronan C-5 Epimerases in Commercial Alginate Production.

Anne Tøndervik, Olav A Aarstad, Randi Aune, Susan Maleki, Philip D Rye, Arne Dessen, Gudmund Skjåk-Bræk, Håvard Sletta

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Immobilization of alginate C-5 epimerases usingApplied and environmental microbiology · 2025
    Article
  3. Advances in alginate biosynthesis: regulation and production inFrontiers in bioengineering and biotechnology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anne TøndervikDepartment of Biotechnology and Nanomedicine, SINTEF Industry, Richard Birkelands vei 3B, N-7034 Trondheim, Norway.
Olav A AarstadDepartment of Biotechnology and Food Science, Norwegian University of Science and Technology, NTNU, Sem Sælands vei 6-8, N-7491 Trondheim, Norway.
Randi AuneDepartment of Biotechnology and Nanomedicine, SINTEF Industry, Richard Birkelands vei 3B, N-7034 Trondheim, Norway.
Susan MalekiDepartment of Biotechnology and Nanomedicine, SINTEF Industry, Richard Birkelands vei 3B, N-7034 Trondheim, Norway.
Philip D RyeAlgiPharma AS, Industriveien 33, N-1337 Sandvika, Norway.ORCID 0000-0001-7762-3300
Arne DessenAlgiPharma AS, Industriveien 33, N-1337 Sandvika, Norway.
Gudmund Skjåk-BrækDepartment of Biotechnology and Food Science, Norwegian University of Science and Technology, NTNU, Sem Sælands vei 6-8, N-7491 Trondheim, Norway.
Håvard SlettaDepartment of Biotechnology and Nanomedicine, SINTEF Industry, Richard Birkelands vei 3B, N-7034 Trondheim, Norway.
SINTEF · NOAlgiPharma (Norway) · NONorwegian University of Science and Technology · NO

Funding

The Research Council of Norway 228542/O30
6 · The paper itself

Abstract

Alginates are one of the major polysaccharide constituents of marine brown algae in commercial manufacturing. However, the content and composition of alginates differ according to the distinct parts of these macroalgae and have a direct impact on the concentration of guluronate and subsequent commercial value of the final product. The

Indexed as

FermentationAcinetobacter baumanniiAlginatesAnti-Bacterial AgentsAscophyllumBacterial ProteinsCarbohydrate EpimerasesHexuronic AcidsIndustrial MicrobiologyLaminariaMicrobial Sensitivity TestsMolecular WeightPhaeophyceaePseudomonas aeruginosaPseudomonas fluorescensSeaweedAlginatesAnti-Bacterial AgentsBacterial ProteinsCarbohydrate Epimerasesguluronic acidHexuronic Acidsmannuronan c-5-epimeraseguluronate oligomersmannuronan C-5 epimerasespotentiation of antibiotic effectseaweed and bacterial alginate

Identifiers

PMID33218095
PMCPMC7698916
OpenAlexW3106281412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.