Evidence map›Paper›PMID 33218080›Full record

ArticleMolecules (Basel, Switzerland)2020

Effect of Fermentation Time on Antioxidant and Anti-Ageing Properties of Green Coffee Kombucha Ferments.

Nizioł-Łukaszewska Zofia, Ziemlewska Aleksandra, Bujak Tomasz, Zagórska-Dziok Martyna, Zarębska Magdalena, Hordyjewicz-Baran Zofia, Wasilewski Tomasz

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  12. Kombucha: Challenges for Health and Mental Health.Foods (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nizioł-Łukaszewska ZofiaDepartment of Technology of Cosmetic and Pharmaceutical Products, Medical College, University of Information Technology and Management in Rzeszow, Kielnarowa 386a, 36-020 Tyczyn, Poland.ORCID 0000-0001-6789-3972
Ziemlewska AleksandraDepartment of Technology of Cosmetic and Pharmaceutical Products, Medical College, University of Information Technology and Management in Rzeszow, Kielnarowa 386a, 36-020 Tyczyn, Poland.ORCID 0000-0001-8871-8911
Bujak TomaszDepartment of Technology of Cosmetic and Pharmaceutical Products, Medical College, University of Information Technology and Management in Rzeszow, Kielnarowa 386a, 36-020 Tyczyn, Poland.ORCID 0000-0003-2140-5966
Zagórska-Dziok MartynaDepartment of Technology of Cosmetic and Pharmaceutical Products, Medical College, University of Information Technology and Management in Rzeszow, Kielnarowa 386a, 36-020 Tyczyn, Poland.
Zarębska MagdalenaŁUKASIEWICZ Research Network-Institute of Heavy Organic Synthesis "Blachownia", Energetykow 9, 47-225 Kedzierzyn-Kozle, Poland.
Hordyjewicz-Baran ZofiaŁUKASIEWICZ Research Network-Institute of Heavy Organic Synthesis "Blachownia", Energetykow 9, 47-225 Kedzierzyn-Kozle, Poland.ORCID 0000-0003-4038-4232
Wasilewski TomaszDepartment of Industrial Chemistry, University of Technology and Humanities in Radom, Chrobrego 27, 26-600 Radom, Poland.ORCID 0000-0002-0498-6415

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kombucha, also known as the Manchurian mushroom, is a symbiotic culture of bacteria and yeast, the so-called SCOBY. This paper presents a comprehensive evaluation of the ferments obtained from green coffee beans after different fermentation times with kombucha. Results for the ferments were compared to the green coffee extract that was not fermented. In this study, the antioxidant potential of obtained ferments was analyzed by assessing the scavenging of external and intracellular free radicals and the assessment of superoxide dismutase activity. Cytotoxicity of ferments on keratinocyte and fibroblast cell lines was assessed as well as anti-aging properties by determining their ability to inhibit the activity of collagenase and elastase enzymes. In addition, the composition of the obtained ferments and the extract was determined, as well as their influence on skin hydration and transepidermal water loss (TEWL) after application of samples on the skin. It has been shown that the fermentation time has a positive effect on the content of bioactive compounds and antioxidant properties. The highest values were recorded for the tested samples after 28 days of fermentation. After 14 days of the fermentation process, it was observed that the analyzed ferments were characterized by low cytotoxicity to keratinocytes and fibroblasts. On the other hand, the short fermentation time of 7 days had a negative effect on the properties of the analyzed ferments. The obtained results indicate that both green coffee extracts and ferments can be an innovative ingredient of cosmetic products.

Indexed as

FermentationKombucha TeaAntioxidantsBiphenyl CompoundsCell SurvivalCoffeeCollagenasesFibroblastsFlavonoidsFluorescenceHaCaT CellsHumansIntracellular SpaceKineticsLimit of DetectionMatrix Metalloproteinase Inhibitors1,1-diphenyl-2-picrylhydrazylAntioxidantsBiphenyl CompoundsCoffeeCollagenasesFlavonoidsKombucha TeaMatrix Metalloproteinase InhibitorsOxazinesPancreatic ElastasePhenolsPicratesReactive Oxygen SpeciesresazurinSuperoxide DismutaseXanthenesantioxidant activityfermentgreen coffeekombuchamatrix metallopeptidases

Identifiers

PMID33218080
PMCPMC7698870

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.