Evidence map›Paper›PMID 33218066›Full record

ReviewMarine drugs2020

Potential Anti-Aging Substances Derived from Seaweeds.

Lei Cao, Sang Gil Lee, Kwon Taek Lim, Hyeung-Rak Kim

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Counteracting Skin Aging In Vitro by Phytochemicals.Journal of cellular and molecular medicine · 2025
    Article
  4. Article
  5. Regulatory effects ofHeliyon · 2024
    Article
  6. Article
  7. Review
  8. A Pectic Polysaccharide fromAntioxidants (Basel, Switzerland) · 2023
    Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lei CaoInstitute of Marine Life Sciences, Pukyong National University, Busan 48513, Korea.
Sang Gil LeeDepartment of Food Science and Nutrition, Pukyong National University, Busan 48513, Korea.
Kwon Taek LimDepartment of Display Science and Engineering, Pukyong National University, Busan 48513, Korea.ORCID 0000-0002-7023-6057
Hyeung-Rak KimDepartment of Food Science and Nutrition, Pukyong National University, Busan 48513, Korea.
Pukyong National University · KR

Funding

National Research Foundation of Korea 2019R1I1A3A0105969012
6 · The paper itself

Abstract

Aging is a major risk factor for many chronic diseases, such as cancer, cardiovascular disease, and diabetes. The exact mechanisms underlying the aging process are not fully elucidated. However, a growing body of evidence suggests that several pathways, such as sirtuin, AMP-activated protein kinase, insulin-like growth factor, autophagy, and nuclear factor erythroid 2-related factor 2 play critical roles in regulating aging. Furthermore, genetic or dietary interventions of these pathways can extend lifespan by delaying the aging process. Seaweeds are a food source rich in many nutrients, including fibers, polyunsaturated fatty acids, vitamins, minerals, and other bioactive compounds. The health benefits of seaweeds include, but are not limited to, antioxidant, anti-inflammatory, and anti-obese activities. Interestingly, a body of studies shows that some seaweed-derived extracts or isolated compounds, can modulate these aging-regulating pathways or even extend lifespans of various animal models. However, few such studies have been conducted on higher animals or even humans. In this review, we focused on potential anti-aging bioactive substances in seaweeds that have been studied in cells and animals mainly based on their anti-aging cellular and molecular mechanisms.

Indexed as

AgingAnimalsBiological ProductsCellular SenescenceHumansSeaweedSignal TransductionBiological Productsanti-agingbioactivemacroalgaeseaweedssenescence

Identifiers

PMID33218066
PMCPMC7698806
OpenAlexW3101779048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.