Evidence map›Paper›PMID 33218042›Full record

ArticleInternational journal of molecular sciences2020

Scopolin Prevents Adipocyte Differentiation in 3T3-L1 Preadipocytes and Weight Gain in an Ovariectomy-Induced Obese Mouse Model.

Eunkuk Park, Chang Gun Lee, Jeonghyun Kim, Eunguk Lim, Subin Yeo, Seon-Yong Jeong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eunkuk ParkDepartment of Medical Genetics, Ajou University School of Medicine, Suwon 16499, Korea.ORCID 0000-0002-1928-5531
Chang Gun LeeDepartment of Medical Genetics, Ajou University School of Medicine, Suwon 16499, Korea.ORCID 0000-0002-2031-0802
Jeonghyun KimDepartment of Medical Genetics, Ajou University School of Medicine, Suwon 16499, Korea.
Eunguk LimDepartment of Medical Genetics, Ajou University School of Medicine, Suwon 16499, Korea.
Subin YeoNine B Company, Daejeon 34121, Korea.
Seon-Yong JeongDepartment of Medical Genetics, Ajou University School of Medicine, Suwon 16499, Korea.ORCID 0000-0002-0625-3530
Ajou University · KR

Funding

National Research Foundation of Korea (NRF) grant 2020R1F1A1075524National Research Foundation of Korea (NRF) grant 2020R1I1A1A01069641
6 · The paper itself

Abstract

Obesity is prevalent in modern human societies. We examined the anti-obesity effects of scopolin on adipocyte differentiation in preadipocyte 3T3-L1 cells and weight loss in an ovariectomy (OVX)-induced obese mouse model. Scopolin inhibited adipocyte differentiation and lipid accumulation in the preadipocyte cells by suppressing the transcription of adipogenic-related factors, including adiponectin (

Indexed as

ObesityOvariectomy3T3-L1 CellsAdipocytesAnimalsCell DifferentiationCoumarinsFemaleGene Expression RegulationGlucosidesMiceTranscription, GeneticCoumarinsGlucosidesscopolinadipogenesisanti-obesity effectobesityOVX-induced obese micescopolin

Identifiers

PMID33218042
PMCPMC7698923
OpenAlexW3104495488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.