ArticleBiology2020
Allergies to Titanium Dental Implants: What Do We Really Know about Them? A Scoping Review.
Article in Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Clinical behavior of two-piece zirconia implants. A systematic review.Medicina oral, patologia oral y cirugia bucal · 2025Pooled it
- Titanium and Other Metal Hypersensitivity Diagnosed by MELISA® Test: Follow-Up Study.BioMed research international · 2021Trial
- Assessment of ion release, cytotoxicity, and potential systemic toxicity of titanium dental alloy.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Multivariate Analysis of the Survival Rates and Risk Factors of One-Piece Zirconia Implants Supporting Single Crowns or Fixed Dental Prostheses: A Retrospective Cohort Study with Follow-Up Periods of up to 8 Years.Dentistry journal · 2026Article
- Autonomous Implants.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Article
- Tailoring Cell Behavior and Antibacterial Properties on Zirconia Biomaterials through Femtosecond Laser-Induced Micropatterns and Nanotopography.ACS applied materials & interfaces · 2025Article
- Treatment strategies for dental implant removal: A literature review.The Japanese dental science review · 2024Review
- Fracture Resistance of a Bone-Level Two-Piece Zirconia Oral Implant System-The Influence of Artificial Loading and Hydrothermal Aging.Journal of functional biomaterials · 2024Article
- Application of density functional theory for evaluating the mechanical properties and structural stability of dental implant materials.BMC oral health · 2023Article
- Biomaterials as Implants in the Orthopedic Field for Regenerative Medicine: Metal versus Synthetic Polymers.Polymers · 2023Review
- Metal hypersensitivity in hip, knee and spine surgery.Postepy dermatologii i alergologii · 2023Review
- Molybdenum as a Potential Biocompatible and Resorbable Material for Osteosynthesis in Craniomaxillofacial Surgery-An In Vitro Study.International journal of molecular sciences · 2022Article
- Metal Allergy: State-of-the-Art Mechanisms, Biomarkers, Hypersensitivity to Implants.Journal of clinical medicine · 2022Review
- Evaluation of the Biocompatibility and Osteogenic Properties of Metal Oxide Coatings Applied by Magnetron Sputtering as Potential Biofunctional Surface Modifications for Orthopedic Implants.Materials (Basel, Switzerland) · 2022Article
- Biocompatibility of ZrOMaterials (Basel, Switzerland) · 2022Article
- Pilot Study and Preliminary Results of Biodegradable Intramedullary Nailing of Forearm Fractures in Children.Children (Basel, Switzerland) · 2022Article
- Long term follow-up of a full- arch rehabilitation with an implant-supported overdenture on four zirconia implants and a zirconia bar. A case report.Journal of clinical and experimental dentistry · 2022Article
- Making Hardware Removal Unnecessary by Using Resorbable Implants for Osteosynthesis in Children.Children (Basel, Switzerland) · 2022Review
- Pre-Competition Oral Findings in Danish Sport Horses and Ponies Competing at High Level.Animals : an open access journal from MDPI · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this scoping review was to describe the current state of knowledge and understanding of allergies to titanium dental implants. A scoping review was conducted following the Prisma Extension for Scoping Reviews checklist. An electronic search was performed in five databases complemented by manual and grey literature searches. Fifty-two relevant papers were included for final review. Titanium particles can be released from the surfaces of dental implants in a process called tribocorrosion, which may contribute to bone loss due to inflammatory reaction. Diverse mechanisms have been described that may trigger allergy to titanium, as well as the clinical signs that manifest as the allergy develops. Allergies to titanium are uncommon but represent a real possibility that should not be overlooked in patients requiring prosthodontic rehabilitation with dental implants. Allergy can trigger a range of symptoms. Patients who have already been diagnosed with allergies to other metals will be more predisposed to suffering an allergy to titanium. Further investigation is needed in order to measure the true scope of these allergies.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.