Evidence map›Paper›PMID 33217928›Full record

ReviewNutrients2020

Gastroesophageal Reflux Disease and Foregut Dysmotility in Children with Intestinal Failure.

Anna Rybak, Aruna Sethuraman, Kornilia Nikaki, Jutta Koeglmeier, Keith Lindley, Osvaldo Borrelli

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Dilemmas in feeding infants with intestinal failure: a neonatologist's perspective.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Anna RybakDepartment of Gastroenterology, the Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK.ORCID 0000-0002-8233-5490
Aruna SethuramanDepartment of Gastroenterology, the Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK.
Kornilia NikakiWingate Institute of Neurogastroenterology, Blizard Institute, Barts and The London School of Medicine and Dentistry, QMUL, 26 Ashfield Street, Whitechapel, London E1 2AJ, UK.ORCID 0000-0002-8968-8926
Jutta KoeglmeierDepartment of Gastroenterology, the Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK.
Keith LindleyDepartment of Gastroenterology, the Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK.
Osvaldo BorrelliDepartment of Gastroenterology, the Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK.
Great Ormond Street Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal dysmotility is a common problem in a subgroup of children with intestinal failure (IF), including short bowel syndrome (SBS) and pediatric intestinal pseudo-obstruction (PIPO). It contributes significantly to the increased morbidity and decreased quality of life in this patient population. Impaired gastrointestinal (GI) motility in IF arises from either loss of GI function due to the primary disorder (e.g., neuropathic or myopathic disorder in the PIPO syndrome) and/or a critical reduction in gut mass. Abnormalities of the anatomy, enteric hormone secretion and neural supply in IF can result in rapid transit, ineffective antegrade peristalsis, delayed gastric emptying or gastroesophageal reflux. Understanding the underlying pathophysiologic mechanism(s) of the enteric dysmotility in IF helps us to plan an appropriate diagnostic workup and apply individually tailored nutritional and pharmacological management, which might ultimately lead to an overall improvement in the quality of life and increase in enteral tolerance. In this review, we have focused on the pathogenesis of GI dysmotility in children with IF, as well as the management and treatment options.

Indexed as

ChildGastroesophageal RefluxGastrointestinal MotilityGastrointestinal TractHumansIntestinal Pseudo-ObstructionShort Bowel SyndromechildrendysmotilitygastroparesisGERDintestinal failurenutritionpediatric intestinal pseudo-obstruction syndromeshort bowel syndrome

Identifiers

PMID33217928
PMCPMC7698758
OpenAlexW3102627056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.