Evidence map›Paper›PMID 33217925›Full record

ArticleInternational journal of molecular sciences2020

Human Endometrial Carcinogenesis Is Associated with Significant Reduction in Long Non-Coding RNA, TERRA.

Meera Adishesh, Rafah Alnafakh, Duncan M Baird, Rhiannon E Jones, Shannon Simon, Lucy Button, Areege M Kamal, John Kirwan, S Bridget DeCruze, Josephine Drury and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Telomere Transcription inBiomedicines · 2023
    Article
  5. Expression of Cellular and ExtracellularInternational journal of molecular sciences · 2022
    Article
  6. Telomere Targeting Approaches in Cancer: Beyond Length Maintenance.International journal of molecular sciences · 2022
    Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Meera AdisheshLiverpool Women's Hospital NHS Foundation Trust, Liverpool L8 7SS, UK.
Rafah AlnafakhDepartment of Women's and Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Member of Liverpool Health Partners, Liverpool L8 7SS, UK.
Duncan M BairdDivision of Cancer and Genetics, Cardiff University, Cardiff CF14 4XN, UK.ORCID 0000-0001-8408-5467
Rhiannon E JonesDivision of Cancer and Genetics, Cardiff University, Cardiff CF14 4XN, UK.
Shannon SimonDepartment of Women's and Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Member of Liverpool Health Partners, Liverpool L8 7SS, UK.
Lucy ButtonDepartment of Women's and Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Member of Liverpool Health Partners, Liverpool L8 7SS, UK.
Areege M KamalDepartment of Women's and Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Member of Liverpool Health Partners, Liverpool L8 7SS, UK.ORCID 0000-0001-5239-9699
John KirwanLiverpool Women's Hospital NHS Foundation Trust, Liverpool L8 7SS, UK.
S Bridget DeCruzeLiverpool Women's Hospital NHS Foundation Trust, Liverpool L8 7SS, UK.
Josephine DruryDepartment of Women's and Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Member of Liverpool Health Partners, Liverpool L8 7SS, UK.ORCID 0000-0002-2275-6664
Gabriele SaretzkiBiosciences Institute, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
Dharani K HapangamaLiverpool Women's Hospital NHS Foundation Trust, Liverpool L8 7SS, UK.ORCID 0000-0003-0270-0150
University of Liverpool · GBCardiff University · GBNewcastle University · GB

Funding

Cancer Research UK 18246Cancer Research UK 29202Cancer Research UK C17199/A18246/A29202
6 · The paper itself

Abstract

Telomeres are transcribed as long non-coding RNAs called TERRAs (Telomeric repeat containing RNA) that participate in a variety of cellular regulatory functions. High telomerase activity (TA) is associated with endometrial cancer (EC). This study aimed to examine the levels of three TERRAs, transcribed at chromosomes 1q-2q-4q-10q-13q-22q, 16p and 20q in healthy (

Indexed as

Transcription, GeneticAdultAgedAged, 80 and overCarcinogenesisChromosomes, HumanEndometrial NeoplasmsEndometriumFemaleHumansMiddle AgedRNA, Long NoncodingRNA, NeoplasmTelomereTelomere HomeostasisRNA, Long NoncodingRNA, Neoplasmendometrial cancerendometriumlong non-coding RNAtelomerasetelomere lengthtelomeresTERRA

Identifiers

PMID33217925
PMCPMC7698627
OpenAlexW3098240036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.