Evidence map›Paper›PMID 33217807›Full record

ArticleMedicine2020

Comorbid irritable bowel syndrome symptoms and headache have greater association with anxiety than depression: Annual health check-up survey results.

Kousaku Kawashima, Nobuhiko Fukuba, Yusuke Uemura, Kuniko Ota, Hideaki Kazumori, Hiroki Sonoyama, Akihiko Oka, Yasumasa Tada, Yoshiyuki Mishima, Naoki Oshima and 4 more

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Kousaku KawashimaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo.
Nobuhiko FukubaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo.
Yusuke UemuraDepartment of Neurology, Matsue Seikyo General Hospital, 8-8-8 Nishitsuda.
Kuniko OtaDepartment of Neurology, Matsue Seikyo General Hospital, 8-8-8 Nishitsuda.
Hideaki KazumoriDepartment of Internal Medicine.
Hiroki SonoyamaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo.
Akihiko OkaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo.
Yasumasa TadaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo.
Yoshiyuki MishimaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo.
Naoki OshimaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo.
Takafumi YukiDepartment of Internal Medicine II, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo.
Tomoko KatsubeDepartment of Preventive Medicine, Matsue Red Cross Hospital, 200 Horo-machi, Matsue, Shimane.
Yoshikazu KinoshitaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo.
Shunji IshiharaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo.
Shimane University · JPMatsue Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High rates of co-existing irritable bowel syndrome (IBS) and headache have been reported in western countries. We investigated that comorbidity in individuals in Japan, along with anxiety and depression in subjects with and without IBS symptoms and/or headache.This cross-sectional study was performed from April 2012 to January 2013 at the Matsue Seikyo General Hospital Health Check Center. Questionnaires concerning symptoms related to IBS (Rome III) and headache, as well as anxiety/depression score were sent to individuals scheduled to undergo an annual health check-up, then returned during the visit and analyzed in a blinded manner.A total of 2885 individuals returned completed questionnaires and were enrolled, of whom 218 (7.6%) met the IBS criteria. The rates of co-existing headache in subjects with and without IBS symptoms were 44.0% (96/218) and 22.9% (611/2667), respectively, indicating a significantly higher rate of co-existing headache in subjects with as compared to without IBS (odds ratio [OR] 2.65, P < .001). Furthermore, the percentage of subjects with anxiety along with comorbid IBS symptoms and headache was significantly greater as compared to those with IBS (OR 3.01, P = .001) or headache (OR 2.41, P < .001) alone. Unlike anxiety, the percentage of subjects with depression was not significantly different among the IBS/non-headache, non-IBS/headache, and IBS/headache groups.Subjects with IBS symptoms had a higher rate of co-existing headache as compared to those without IBS. Furthermore, those with comorbid IBS symptoms and headache had a greater association with anxiety than with depression, as compared to those with only IBS or headache.

Indexed as

AdultAgedAged, 80 and overAnxietyComorbidityCross-Sectional StudiesDepressionFemaleHeadacheHealth SurveysHumansIrritable Bowel SyndromeJapanMaleMiddle AgedProspective Studies

Identifiers

PMID33217807
PMCPMC7676610
OpenAlexW3102990757

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.