Evidence map›Paper›PMID 33217804›Full record

ArticleMedicine2020

Gancao Xiexin decoction combined with mesalazine in the treatment of ulcerative colitis: A protocol for a systematic review and meta-analysis.

Chun Zhong, Xiaoming Cheng, Bo Jia, PeiYu Xiong, Jinhua Lu, Peixu Zhang, Xinglong Liu, Yunhui Chen

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. World journal of gastroenterology · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chun ZhongSchool of Basic Medical Science, Chengdu University of Traditional Chinese Medicine, Chengdu.
Xiaoming ChengXiangYang Hospital of Traditional Chinese Medicine, Xiangyang, China.
Bo JiaSchool of Basic Medical Science, Chengdu University of Traditional Chinese Medicine, Chengdu.
PeiYu XiongSchool of Basic Medical Science, Chengdu University of Traditional Chinese Medicine, Chengdu.
Jinhua LuSchool of Basic Medical Science, Chengdu University of Traditional Chinese Medicine, Chengdu.
Peixu ZhangSchool of Basic Medical Science, Chengdu University of Traditional Chinese Medicine, Chengdu.
Xinglong LiuSchool of Basic Medical Science, Chengdu University of Traditional Chinese Medicine, Chengdu.ORCID 0000-0003-4946-9371
Yunhui ChenSchool of Basic Medical Science, Chengdu University of Traditional Chinese Medicine, Chengdu.
Chengdu University of Traditional Chinese Medicine · CNXiangyang Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroudUlcerative colitis (UC) is a chronic inflammatory disease that involves the rectum, colon and ileum. Gancao Xiexin decoction (GCXXD) is a classic herbal formula in Shanghanlun. More and more research evidence shows that GCXXD has a certain therapeutic effect on UC. Therefore, we designed this study protocol aim to evaluate the efficacy and safety of GCXXD combine with mesalazine for UC.

methodsWe will systematically search 6 databases, including PubMed, the Cochrane Library, EMBASE, CNKI, VIP, Wang-fang database up to July 2020 to obtain eligible studies. The primary outcomes will focus on the clinical effectiveness. Review Manager 5.3 software will be used for data analysis.

resultsThis study will provide the systematic evidence of UC treated with GCXXD combine with mesalazine.

conclusionThe findings of this meta-analysis will provide evidence to judge whether GCXXD combine with mesalazine is a more effective intervention compare to mesalazine only for patient of UC. INPLASY REGISTRATION NUMBER: INPLASY202080008.

Indexed as

Research DesignAnti-Inflammatory Agents, Non-SteroidalColitis, UlcerativeDrugs, Chinese HerbalDrug Therapy, CombinationHumansMesalamineMeta-Analysis as TopicSystematic Reviews as TopicAnti-Inflammatory Agents, Non-SteroidalDrugs, Chinese HerbalMesalamineXiexin decoction

Identifiers

PMID33217804
PMCPMC7676594
OpenAlexW3047057834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.