Evidence map›Paper›PMID 33217349›Full record

ArticleThe American journal of cardiology2021

Socio-Economic Burden of Myocardial Infarction Among Cancer Patients.

Avirup Guha, Amit Kumar Dey, Sadeer Al-Kindi, P Elliott Miller, Arjun K Ghosh, Amitava Banerjee, Juan Lopez-Mattei, Nihar R Desai, Brijesh Patel, Guilherme H Oliveira and 3 more

Open access · greenAbstract read
In one paragraph

Article in The American journal of cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 2 countries.

Avirup GuhaHarrington Heart and Vascular Institute, Case Western Reserve University, Cleveland, Ohio; Cardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, Ohio.
Amit Kumar DeyNational Heart, Lung and Blood Institute, Bethesda, Maryland.
Sadeer Al-KindiHarrington Heart and Vascular Institute, Case Western Reserve University, Cleveland, Ohio.
P Elliott MillerDivision of Cardiology, Yale University School of Medicine, New Haven, Connecticut; Yale National Clinician Scholars Program, New Haven, Connecticut.
Arjun K GhoshCardio-Oncology Service, Bart's Heart Centre and University College London Hospital, Hatter Cardiovascular Institute, London, United Kingdom.
Amitava BanerjeeInstitute of Health Informatics, University College London, London, United Kingdom.
Juan Lopez-MatteiDepartment of Cardiology, University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, Houston, Texas.
Nihar R DesaiDivision of Cardiology, Yale University School of Medicine, New Haven, Connecticut; Center for Outcomes Research and Evaluation, New Haven, Connecticut.
Brijesh PatelDivision of Cardiology, West Virginia University, Morgantown, West Virginia.
Guilherme H OliveiraCardio-Oncology Program, Division of Cardiovascular Medicine, University of South Florida Morsani College of Medicine and H. Lee Moffitt Cancer Center and Research Institute and, Tampa, Florida.
Marcos de LimaAdult Hematologic Malignancies and Stem Cell Transplant Program, Seidman Cancer Center, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
Michael FradleyCardio-Oncology Program, Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, Pennysylvania.
Daniel AddisonCardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, Ohio; Cancer Control Program, Department of Internal Medicine, Ohio State University Comprehensive Cancer Center, Columbus, Ohio. Electronic address: daniel.addison@osumc.edu.
The Ohio State University Wexner Medical Center · USYale University · USCase Western Reserve University · USNational Heart Lung and Blood Institute · USRoyal London Hospital · GBThe University of Texas MD Anderson Cancer Center · USUniversity College London · GBUniversity Hospitals Seidman Cancer Center · USUniversity of Pennsylvania · USUniversity of South Florida · USWest Virginia University · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
Translational Training Grant in Experimental TherapeuticsK12CA133250 · NCI · OHIO STATE UNIVERSITY · PI WILLIAM E. CARSON, Rosa Lapalombella · 2008 to 2026
$15.0M
NRSA Training CoreTL1TR001864 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$9.9M
NCATS NIH HHS TL1 TR001864NCATS NIH HHS UL1 TR001863NCI NIH HHS K12 CA133250NCI NIH HHS P30 CA016058NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

Cancer patients face a higher risk of future myocardial infarction (MI), even after completion of anticancer therapies. MI is a critical source of physical and financial stress in noncancer patients, but its impacts associated with cancer patients also saddled with the worry (stress) of potential reoccurrence is unknown. Therefore, we aimed to quantify MI's stress and financial burden after surviving cancer and compare to those never diagnosed with cancer. Utilizing cross-sectional national survey data from 2013 to 2018 derived from publicly available United States datasets, the National Health Interview Survey , and economic data from the National Inpatient Sample , we compared the socio-economic outcomes in those with MI by cancer-status. We adjusted for social, demographic, and clinical factors. Overall, 19,504 (10.2%) of the 189,836 National Health Interview Survey responders reported having cancer for more than 1 year. There was an increased prevalence of MI in cancer survivors compared with noncancer patients (8.8% vs 3.2%, p <0.001). MI was associated with increased financial worry, food insecurity, and financial burden of medical bills (p <0.001, respectively); however, concurrent cancer did not seem to be an effect modifier (p >0.05). There was no difference in annual residual family income by cancer status; however, 3 lowest deciles of residual income representing 21.1% cancer-survivor with MI had a residual income of <$9,000. MI continues to represent an immense source of financial and perceived stress. In conclusion, although cancer patients face a higher risk of subsequent MI, this does not appear to advance their reported stress significantly.

Indexed as

Food InsecurityHealth ExpendituresNeoplasmsAdolescentAdultAgedCancer SurvivorsCase-Control StudiesCost of IllnessFemaleFinancial StressHumansMaleMiddle AgedMyocardial InfarctionStress, Psychological

Identifiers

PMID33217349
PMCPMC8406452
OpenAlexW3099972240

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.