ArticleAmerican journal of respiratory and critical care medicine2021
Tissue-Specific Immunopathology in Fatal COVID-19.
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In one paragraph
Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 199 papers, 8 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
199citing papers in PubMed, 8 pooled it
6.7field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
199 citing papers in PubMed, 8 syntheses or guidelines pooled it, 304 citations in OpenAlex.
- Incidence, mortality and risk factors of invasive pulmonary aspergillosis in critically ill patients during the COVID-19 era: a global systematic review and meta-analysis.Annals of clinical microbiology and antimicrobials · 2026Pooled it
- Research progress and perspectives on the application of tyramide signal amplification-based multiplex immunohistochemistry/immunofluorescence: a bibliometrics analysis.Frontiers in oncology · 2024Pooled it
- SARS-CoV-2 persistence and infectivity in COVID-19 corpses: a systematic review.Forensic science, medicine, and pathology · 2023Pooled it
- Findings and inferences from full autopsies, minimally invasive autopsies and biopsy studies in patients who died as a result of COVID19 - A systematic review.Forensic science, medicine, and pathology · 2022Pooled it
- COVID-19 Vasculitis and vasculopathy-Distinct immunopathology emerging from the close juxtaposition of Type II Pneumocytes and Pulmonary Endothelial Cells.Seminars in immunopathology · 2022Pooled it
- Systemic administration of glucocorticoids, cardiovascular complications and mortality in patients hospitalised with COVID-19, SARS, MERS or influenza: A systematic review and meta-analysis of randomised trials.Pharmacological research · 2022Pooled it
- Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19.Scientific reports · 2020Pooled it
- Update of the recommendations of the Sociedade Portuguesa de Cuidados Intensivos and the Infection and Sepsis Group for the approach to COVID-19 in Intensive Care Medicine.Revista Brasileira de terapia intensivaPooled it
- Phase I/II clinical trial of efficacy and safety of EGCG oxygen nebulization inhalation in the treatment of COVID-19 pneumonia patients with cancer.BMC cancer · 2024Trial
- An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE).American journal of respiratory and critical care medicine · 2023Trial
- Early Use of Sarilumab in Patients Hospitalized with COVID-19 Pneumonia and Features of Systemic Inflammation: the SARICOR Randomized Clinical Trial.Antimicrobial agents and chemotherapy · 2022Trial
- Prostacyclin in Intubated Patients with COVID-19 and Severe Endotheliopathy: A Multicenter, Randomized Clinical Trial.American journal of respiratory and critical care medicine · 2022Trial
- Colchicine in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.The Lancet. Respiratory medicine · 2021Trial
- Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.Lancet (London, England) · 2021Trial
- The CCR2 inflammatory pathway is a target for improving severe disease and pulmonary inflammation in experimental COVID-19.Virulence · 2026Article
- Systems genetics analysis reveals immune mediators of coronavirus disease severity in mice.Genetics · 2026Article
- The Acute Respiratory Distress Syndrome (ARDS): epidemiology, etiology, molecular mechanisms, diagnosis and therapeutic strategies.Molecular biomedicine · 2026Review
- Cross-coronavirus host susceptibility loci influence disease severity through immune mediators.bioRxiv : the preprint server for biology · 2026Article
- Targeting PTP4A3 with KVX-053 mitigates alcohol-amplified SARS-CoV-2 spike protein-induced acute lung injury.Frontiers in pharmacology · 2026Article
- High Free IgE and Mast Cell Activation in Long COVID: Mechanisms of Persistent Immune Dysregulation.Life (Basel, Switzerland) · 2025Article
139 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
28 authors at 9 institutions in 3 countries.
David A DorwardCentre for Inflammation Research, Queen's Medical Research Institute, and.ORCID 0000-0002-4658-8829
Clark D RussellCentre for Inflammation Research, Queen's Medical Research Institute, and.ORCID 0000-0002-9873-8243
In Hwa UmSchool of Medicine, University of St. Andrews, St. Andrews, United Kingdom.
Mustafa ElshaniSchool of Medicine, University of St. Andrews, St. Andrews, United Kingdom.ORCID 0000-0002-2724-0325
Stuart D ArmstrongInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0002-3862-1801
Rebekah Penrice-RandalInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0002-0653-2097
Tracey MillarCentre for Clinical Brain Sciences, Chancellor's Building, University of Edinburgh, Edinburgh BioQuarter, Edinburgh, United Kingdom.
Chris E B LerpiniereCentre for Clinical Brain Sciences, Chancellor's Building, University of Edinburgh, Edinburgh BioQuarter, Edinburgh, United Kingdom.
Giulia TagliaviniCentre for Inflammation Research, Queen's Medical Research Institute, and.ORCID 0000-0003-2210-9923
Catherine S HartleyInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0001-9014-1015
Nadine P RandleInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0002-3775-9585
Naomi N GachanjaCentre for Inflammation Research, Queen's Medical Research Institute, and.
Philippe M D PoteyCentre for Inflammation Research, Queen's Medical Research Institute, and.
Xiaofeng DongInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.
Alison M AndersonMortuary Department.
Victoria L CampbellDepartment of Haematology, and.
Alasdair J DuguidDepartment of Haematology, and.
Wael Al QsousDepartment of Pathology, Western General Hospital, Edinburgh, United Kingdom.ORCID 0000-0002-5212-2574
Ralph BouHaidarDepartment of Pathology.
J Kenneth BaillieIntensive Care Unit, and.ORCID 0000-0001-5258-793X
Kevin DhaliwalCentre for Inflammation Research, Queen's Medical Research Institute, and.ORCID 0000-0002-3925-3174
William A WallaceDepartment of Pathology.
Christopher O C BellamyCentre for Inflammation Research, Queen's Medical Research Institute, and.
Sandrine ProstCentre for Inflammation Research, Queen's Medical Research Institute, and.ORCID 0000-0002-0140-7115
Colin SmithCentre for Clinical Brain Sciences, Chancellor's Building, University of Edinburgh, Edinburgh BioQuarter, Edinburgh, United Kingdom.ORCID 0000-0002-4507-5132
Julian A HiscoxInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0002-6582-0275
David J HarrisonDepartment of Pathology.ORCID 0000-0001-9041-9988
Christopher D LucasCentre for Inflammation Research, Queen's Medical Research Institute, and.ORCID 0000-0002-7523-0295
Centre for Inflammation Research · GBUniversity of Liverpool · GBUniversity of Edinburgh · GBUniversity of St Andrews · GBEdinburgh Royal Infirmary · GBAgency for Science, Technology and Research · SGCincinnati College of Mortuary Science · USRoslin Institute · GBWestern General Hospital · GB
Funding
Chief Scientist Office COV/EDI/20/10Medical Research Council MC_PC_19025Medical Research Council MC_PC_19059Medical Research Council MR/L016400/1Medical Research Council MR/V028790/1Wellcome Trust
Abstract
PubMed holds no abstract for this paper.
Indexed as
AgedAged, 80 and overAutopsyBiopsyCOVID-19COVID-19 Nucleic Acid TestingFemaleFluorescent Antibody TechniqueHumansInflammationLungMaleMultiple Organ FailureSARS-CoV-2Severity of Illness IndexautopsyCOVID-19inflammationlungmacrophages
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.