Evidence map›Paper›PMID 33216708›Full record

ArticleFood additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment2021

Human aflatoxin exposure in Uganda: Estimates from a subset of the 2011 Uganda AIDS indicator survey (UAIS).

Nicholas C Zitomer, Abigael O Awuor, Marc-Alain Widdowson, Johnni H Daniel, Maya R Sternberg, Michael E Rybak, Edward K Mbidde

Open access · greenAbstract read
In one paragraph

Article in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Aflatoxin BJournal of fungi (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Nicholas C ZitomerCenters for Disease Control and Prevention (CDC), National Center for Environmental Health (NCEH) , Division of Laboratory Sciences (DLS), Atlanta, Georgia.ORCID https://orcid.org/0000-0002-3900-4282
Abigael O AwuorCDC-Kenya, Center for Global Health (CGH) , Division of Global Health Protection, Nairobi, Kenya.
Marc-Alain WiddowsonCDC-Kenya, Center for Global Health (CGH) , Division of Global Health Protection, Nairobi, Kenya.ORCID https://orcid.org/0000-0002-0682-6933
Johnni H DanielCDC, NCEH, Division of Environmental Health Hazards & Health Effects , Atlanta, Georgia.
Maya R SternbergCenters for Disease Control and Prevention (CDC), National Center for Environmental Health (NCEH) , Division of Laboratory Sciences (DLS), Atlanta, Georgia.
Michael E RybakCenters for Disease Control and Prevention (CDC), National Center for Environmental Health (NCEH) , Division of Laboratory Sciences (DLS), Atlanta, Georgia.ORCID https://orcid.org/0000-0003-1650-8581
Edward K MbiddeUganda Virus Research Institute , Entebbe, Uganda.
Centers for Disease Control and Prevention · USCenters for Disease Control and Prevention · KENational Center for Environmental Health · USUganda Virus Research Institute · UG

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Aflatoxins are carcinogenic mycotoxins that contaminate a variety of crops worldwide. Acute exposure can cause liver failure, and chronic exposure can lead to stunting in children and liver cancer in adults. We estimated aflatoxin exposure across Uganda by measuring a serum biomarker of aflatoxin exposure in a subsample from the 2011 Uganda AIDS Indicator Survey, a nationally representative survey of HIV prevalence, and examined its association with geographic, demographic, and socioeconomic variables. We analysed a subsample of 985 serum specimens selected among HIV-negative participants from 10 survey-defined geographic regions for serum aflatoxin B1-lysine (AFB1-lys) by use of isotope dilution LC-MS/MS and calculated results normalised to serum albumin. We used statistical techniques for censored data to estimate geometric means (GMs), standard deviations, and percentiles. We detected serum AFB1-lys in 71.7% of specimens (LOD = 0.5 pg/mg albumin). Unadjusted GM AFB1-lys (pg/mg albumin) was 1.33 (95% CI: 1.21-1.47). Serum AFB1-lys was higher in males (GM: 1.57; 95% CI: 1.38-1.80) vs. females (GM: 1.12; 95% CI: 0.97-1.30) (

Indexed as

Blood Specimen CollectionHealth SurveysAcquired Immunodeficiency SyndromeAdolescentAdultAflatoxin B1BiomarkersEnvironmental ExposureFemaleHumansMaleMiddle AgedYoung AdultAflatoxin B1Biomarkersaflatoxinaflatoxin-lysine biomarkerhuman exposuremycotoxinUganda

Identifiers

PMID33216708
PMCPMC12168092
OpenAlexW3100825126

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.