ReviewBiological trace element research2021
Copper Nanoparticles as Growth Promoter, Antioxidant and Anti-Bacterial Agents in Poultry Nutrition: Prospects and Future Implications.
Review in Biological trace element research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 59 citations in OpenAlex.
- Novel in ovo application of green-synthesized FeScientific reports · 2026Article
- Nanoparticle-Based Approaches for Enhancing In Vitro Fertilization in Animal Reproduction.International journal of molecular sciences · 2026Review
- Effects of Dietary Nano-Composite of Copper and Carbon on Antioxidant Capacity, Immunity, and Cecal Microbiota of Weaned Ira White Rabbits.Animals : an open access journal from MDPI · 2025Article
- Engineering copper and copper-based materials for a post-antibiotic era.Frontiers in bioengineering and biotechnology · 2025Review
- Counteractive Effects of Copper Nanoparticles and Betacellulin on Ovarian Cells.Nanomaterials (Basel, Switzerland) · 2024Article
- Impacts of Nano-Composite of Copper and Carbon on Intestinal Luminal Micro-Ecosystem and Mucosal Homeostasis of Yellow-Feather Broilers.Microorganisms · 2024Article
- Copper Nanoparticle Loaded Electrospun Patches for Infected Wound Treatment: From Development to In-Vivo Application.Polymers · 2024Article
- Development of two highly sensitive and selective sensor-assisted fluorescence immunoassays for trace determination of copper residues in food samples.RSC advances · 2023Article
- Efficacy of zinc oxide and copper oxide nanoparticles on virulence genes of avian pathogenic E. coli (APEC) in broilers.BMC veterinary research · 2023Article
- Mechanistic insights of Euphorbia milii des moul mediated biocompatible and non-cytotoxic, antimicrobial nanoparticles: an answer to multidrug resistant bacteria.World journal of microbiology & biotechnology · 2023Article
- Metal- and antibiotic-resistant heterotrophic plate count bacteria from a gold mine impacted river: the Mooi River system, South Africa.Environmental science and pollution research international · 2023Article
- Dietary supplementation with nano-composite of copper and carbon on growth performance, immunity, and antioxidant ability of yellow-feathered broilers.Journal of animal science · 2023Article
- The efficacy of metal nanocomposite (FeBMC veterinary research · 2022Article
- Hot-melt extruded copper sulfate affects the growth performance, meat quality, and copper bioavailability of broiler chickens.Animal bioscience · 2022Article
- Copper-containing nanoparticles: Mechanism of antimicrobial effect and application in dentistry-a narrative review.Frontiers in surgery · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Copper (Cu) is a vital trace mineral involved in many physiological functions of the body. In the poultry industry, copper sulfate is being used as a major source of Cu. Copper in the bulk form is less available in the body, and much of its amount excreted out with feces causing environmental pollution and economic loss. The application of nanotechnology offers promise to address these issues by making nanoparticles. Copper nanoparticles (Cu-NP) are relatively more bioavailable due to their small size and high surface to volume ratio. Although, there is limited research on the use of Cu-NP in the poultry industry. Some researchers have pointed out the importance of Cu-NP as an effective alternative of chemical, anti-bacterial agents, and growth promoters. The effect of Cu-NP depends on their size, dose rate and the synthesis method. Apart from there, high bioavailability Cu-NP exhibited positive effects on the immunity of the birds. However, some toxic effects of Cu-NP have also been reported. Further investigations are essentially required to provide mechanistic insights into the role of Cu-NP in the avian physiology and their toxicological properties. This review aims to highlight the potential effects of Cu-NP on growth, immune system, antioxidant status, nutrient digestibility, and feed conversion ratio in poultry. Moreover, we have also discussed the future implications of Cu-NP as a growth promoter and alternative anti-bacterial agents in the poultry industry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.