Observational studyJournal of clinical monitoring and computing2021
Prognostic value and time course evolution left ventricular global longitudinal strain in septic shock: an exploratory prospective study.
Observational study in Journal of clinical monitoring and computing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03663192 (Strain Echocardiography During Septic Shock), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Strain Echocardiography During Septic Shock : an Observational Pilot Study
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Prognostic value of left ventricular ejection fraction and global longitudinal strain for short-term mortality in sepsis: a systematic review and meta-analysis.Journal of cardiothoracic surgery · 2026Pooled it
- Sepsis-induced myocardial dysfunction diagnosed with strain versus non-strain echocardiography parameters: incidence, evolution and association with prognosis.Annals of intensive care · 2025Article
- Left ventricular systolic longitudinal strain in mechanically ventilated patients in the intensive care unit: assessment of global and chamber reproducibility.Intensive care medicine experimental · 2025Article
- Association between left ventricular systolic function parameters and myocardial injury, organ failure and mortality in patients with septic shock.Annals of intensive care · 2024Article
- Seven-day and In-hospital Mortality According to Left and Right Ventricular Dysfunction in Patients With Septic Shock.Korean circulation journal · 2023Article
- Mitral annular plane systolic excursion for assessing left ventricular systolic dysfunction in patients with septic shock.BJA open · 2023Article
- Left ventricular longitudinal wall fractional shortening accurately predicts longitudinal strain in critically ill patients with septic shock.Annals of intensive care · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our main objective was to describe the course of GLS during the first days of septic shock and to assess the agreement between GLS values and longitudinal strain measured in apical four chambers. A prospective observational single centre study was conducted at the Nimes University Hospital's ICU. All patients admitted for a diagnosis of septic shock without pre-existing heart disease were eligible. Echocardiography (LVEF and GLS) was performed on the first day, and repeated once between day 3 and day 5 then once between day 6 and day 8. We enrolled 40 consecutive patients. Four patients were excluded. In overall population, GLS at T1 was impaired (- 11.0%, IQR(interquartile range) [- 15; - 10]). On T2 exams, a significant improvement of the GLS (- 11% vs - 16% p = 0.02) was observed whereas LVEF remained stable over time. A good agreement between GLS and longitudinal strain measured on a four chambers view was found. Based on the Bland and Altman method, the mean of differences for T1 exams was 0.1 (95% CI [- 0.6; 0.8]) with limits of agreement ranging from - 4 to 4. Myocardial strain is depressed at the early phase of septic shock and improves over time. A single measurement of LS4C view appears sufficient at bedside.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.