ReviewActa neurochirurgica2021
Meningiomas from a developmental perspective: exploring the crossroads between meningeal embryology and tumorigenesis.
Review in Acta neurochirurgica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- A systematic review and meta-analysis of the association between cyproterone acetate and intracranial meningiomas.Scientific reports · 2022Pooled it
- Distinct clinical characteristics and prognostic factors of pediatric meningiomas in a 10-year cohort of 198 patients.Neurosurgical review · 2026Article
- MIB-1 index predicts low recurrence risk after subtotal resection of meningiomas: a retrospective study of 505 patients.Neurosurgical review · 2026Article
- From intraosseous meningioma and ossified metaplastic meningioma to osteomeningioma: a novel voxel-based, atlas-normalized MRI framework for the radiological classification of skull-involving meningiomas.Neuroimage. Reports · 2026Article
- Voxel-based spatial distribution of intracranial meningioma subtypes and their relationship to radiogenomic maps.Brain communications · 2026Article
- Extending voxel-based lesion mapping to neurosurgical oncology: applications in intracranial meningiomas.Frontiers in oncology · 2026Article
- Article
- Prevalence, natural history and surgical outcome of spinal meningiomas in NF2-related schwannomatosis.Journal of neuro-oncology · 2025Observational
- Review
- A novel rotation and scale-invariant deep learning framework leveraging conical transformers for precise differentiation between meningioma and solitary fibrous tumor.Journal of pathology informatics · 2025Article
- Cas9 Mouse Model of Skull Base Meningioma Driven by Combinational Gene Inactivation in Meningeal Cells.CNS neuroscience & therapeutics · 2025Article
- Tumour-associated macrophages in human meningiomas.PloS one · 2025Article
- Single versus multiple reoperations for recurrent intracranial meningiomas.Journal of neuro-oncology · 2024Article
- Stem-like signatures in human meningioma cells are under the control of CXCL11/CXCL12 chemokine activity.Neuro-oncology · 2023Article
- Review
- Article
- Pediatric meningiomas: A literature review and diagnostic update.Neuro-oncology advances · 2023Article
- Pediatric Meningiomas: Current Insights on Pathogenesis and Management.Acta neurochirurgica. Supplement · 2023Review
- Editorial: Meningioma: From basic research to clinical translational study, volume II.Frontiers in oncology · 2023Article
- Clinical significance of NF2 alteration in grade I meningiomas revisited; prognostic impact integrated with extent of resection, tumour location, and Ki-67 index.Acta neuropathologica communications · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meningiomas are tumors arising from the meninges and represent the most frequent central nervous system tumors in adults. Recent large-scale genetic studies and preclinical meningioma mouse modelling led to a better comprehension of meningioma development and suggested evidences of close relationships between meningeal embryology and tumorigenesis. In this non-systematic review, we summarize the current knowledge on meningeal embryology and developmental biology, and illustrate how meningioma tumorigenesis is deeply related to meningeal embryology, concerning the potential cell of origin, the role of reactivation of embryonic stem cells, the influence of the embryonic tissue of origin, and the parallelism between topography-dependant molecular pathways involved in normal meninges and in meningioma development. Our study emphasizes why future studies on meningeal embryology are mandatory to affine our comprehension of mechanisms underlying meningioma initiation and development.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.