Evidence map›Paper›PMID 33216185›Full record

Observational studyEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Balance disorders as potential confounders associated with an increased risk of acute cerebrovascular accidents.

Emilio Domínguez-Durán, Irene Mármol-Szombathy, María José López-Urbano, Ana Palomo-Sánchez, Fátima Alarcón-Balanza, Estela Palmero-Olmo, Ana Nogales-Nieves, Pablo Otero-Aguilar, Blas Poyatos-Poyatos, Manuel Torres-Rodríguez and 7 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Emilio Domínguez-DuránUnidad de Gestión Sanitaria de Otorrinolaringología, Hospital Universitario Virgen Macarena, Avenida Doctor Fedriani 3, 41009, Sevilla, Spain. emilio.dominguez.sspa@juntadeandalucia.es.ORCID http://orcid.org/0000-0003-0088-5817
Irene Mármol-SzombathyUnidad de Gestión Sanitaria de Otorrinolaringología, Hospital Universitario Virgen Macarena, Avenida Doctor Fedriani 3, 41009, Sevilla, Spain.
María José López-UrbanoDistrito Sanitario de Atención Primaria de Sevilla, Sevilla, Spain.
Ana Palomo-SánchezDistrito Sanitario de Atención Primaria de Sevilla, Sevilla, Spain.
Fátima Alarcón-BalanzaCentro de Salud "Pino Montano A", Sevilla, Spain.
Estela Palmero-OlmoDistrito Sanitario de Atención Primaria "Sevilla Norte", Sevilla, Spain.
Ana Nogales-NievesCentro de Salud "Polígono Norte",, Sevilla, Spain.
Pablo Otero-AguilarCentro de Salud "Mercedes Navarro", Sevilla, Spain.
Blas Poyatos-PoyatosCentro de Salud "Polígono Norte",, Sevilla, Spain.
Manuel Torres-RodríguezCentro de Salud "El Mirador" San José de la Rinconada, Sevilla, Spain.
María Teresa Manjón-ColladoCentro de Salud "El Mirador" San José de la Rinconada, Sevilla, Spain.
Beatriz Bullón-FernándezCentro de Salud "Pino Montano A", Sevilla, Spain.
Manuela Campos-HolguínCentro de Salud "Alamillo", Sevilla, Spain.
Feliciana Valle-MartínCentro de Salud "Alamillo", Sevilla, Spain.
Patricia Medina-MorenoCentro de Salud "Ronda Histórica", Sevilla, Spain.
Antonio Mora-QuinteroCentro de Salud "Ronda Histórica", Sevilla, Spain.
Serafín Sánchez-GómezUnidad de Gestión Sanitaria de Otorrinolaringología, Hospital Universitario Virgen Macarena, Avenida Doctor Fedriani 3, 41009, Sevilla, Spain.
Consejería de Salud y Consumo · ESAgencia de Evaluación de Tecnologías Sanitarias · ESHospital Universitario Virgen Macarena · ESDepartamento de Salud · ESServicio Navarro de Salud · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is a higher risk of stroke after suffering from balance disorders (BDs) such as vertigo or dizziness. The causal relationship remains unclear due to the limited scope of the existing studies and the high prevalence of cardiovascular risk factors (CVRFs) in BD patients. The objective of this study is to clarify the role that BDs seem to have in the development of acute cerebrovascular accidents (ACAs).

methodsThis is an observational prospective study. The CVRFs and demographic factors of a sample of our population were noted. Five clusters of patients were tracked over the course of 2 years to detect and diagnose BDs and ACAs. The causal relationships between the CVRFs, BDs and ACAs were analyzed in a univariate analysis. A logistic regression multivariant analysis was performed on those variables that reached statistical significance.

resultsThe sample included 7886 participants and 31 ACAs were recorded. CVRFs that reached statistical significance included age ≥ 60, hypertension, diabetes mellitus, dyslipidemia, ischemic heart disease, atrial fibrillation and previous ACAs. The relationship between BDs and ACAs always reached statistical significance, regardless of how the BD variable was defined. Five different multivariate analyses were performed, but in none of them did the BD variables significantly reduce the deviance and thus, they were not taken into account when building the final model.

conclusionThis study shows that BDs are probably confounders that are closely linked to other CVRFs and they are also useful red flags to identify patients at a higher risk of suffering from ACAs.

Indexed as

HypertensionStrokeDizzinessHumansProspective StudiesRisk FactorsDizzinessRisk factorsStrokeVertigo

Identifiers

PMID33216185
OpenAlexW3100573729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.