Evidence map›Paper›PMID 33216183›Full record

ArticleArchives of orthopaedic and trauma surgery2022

Difficult life events affect lower extremity illness.

Aresh Al Salman, Michael Z Khatiri, Teun Cremers, David Ring, Jacob E Thomas, Amirreza Fatehi

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Article in Archives of orthopaedic and trauma surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aresh Al SalmanDepartment of Surgery and Perioperative Care, Dell Medical School, 1601 Trinity St Bldg B, Austin, TX, 78712, US.
Michael Z KhatiriDepartment of Surgery and Perioperative Care, Dell Medical School, 1601 Trinity St Bldg B, Austin, TX, 78712, US.
Teun CremersDepartment of Surgery and Perioperative Care, Dell Medical School, 1601 Trinity St Bldg B, Austin, TX, 78712, US.
David RingDepartment of Surgery and Perioperative Care, Dell Medical School, 1601 Trinity St Bldg B, Austin, TX, 78712, US. David.ring@austin.utexas.edu.ORCID http://orcid.org/0000-0002-6506-4879
Jacob E ThomasDept. of Kinesiology and Health Education, Health Behavior and Health Education Program, The University of Texas at Austin, Austin, US.
Amirreza FatehiDepartment of Surgery and Perioperative Care, Dell Medical School, 1601 Trinity St Bldg B, Austin, TX, 78712, US.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGiven the relationship between psychological distress and activity tolerance (capability), a stressful life event might diminish accommodation, increase symptoms, and induce a person to seek specialty care. As a first step to investigate this possibility, this study addressed whether difficult life events are associated with greater activity intolerance and pain intensity.

methodsA cohort of 127 patients seeking specialty care for lower extremity symptoms completed questionnaires that inquired about difficult life events within the last 12 months as derived from the Holmes Rahe Life Stress Inventory, and recorded pain intensity on an 11-point ordinal scale, activity tolerance [Patient Reported Outcomes Measurement Information System Physical Function Computer Adaptive Test (CAT)], symptoms of anxiety (GAD-2; 2 item version of the Generalized Anxiety Disorder questionnaire), symptoms of depression (PROMIS Depression CAT), self-efficacy when in pain (Pain Self-Efficacy Questionnaire, 2 question version), and demographics. The treating clinician indicated if the disease was established (e.g. arthritis) or relatively new (e.g. sprain/strain). Bivariate and multivariable analyses sought factors associated with activity intolerance and pain intensity.

resultsGreater activity intolerance was associated with difficult life events in bivariate analyses (t = 2.13, MD = 3.18, 95% C.I. = 0.22-6.13, p = 0.04) and in multivariable analyses that excluded symptoms of depression. Greater pain intensity was not associated with difficult life events, but was associated with surgeon rating of established disease (β = 1.20, 95% C.I. = 0.33-2.08, p < 0.01), greater symptoms of anxiety (MD = 3.35, s = 1.72; ρ = 0.30, p < 0.01), and less education (β =  - 1.06, 95% C.I. =  - 1.94- - 0.18, p = 0.02) (no college degree).

conclusionWhen a musculoskeletal specialist identifies less activity tolerance (less capability) than anticipated for a given injury or pathology, they can anticipate a potential difficult life event, and expect alleviation of symptoms and improved capability as the stress is ameliorated with time and support. Specialists can be prepared to direct people to community or professional support if requested.

Indexed as

Musculoskeletal PainCross-Sectional StudiesDisability EvaluationHumansLower ExtremityPatient Reported Outcome MeasuresDifficult life eventsGradual-onset diseaseLower extremity illnessPatient reported outcome measures

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.