Evidence map›Paper›PMID 33215809›Full record

ArticleHIV medicine2021

Healthcare delivery for HIV-positive people with tuberculosis in Europe.

A K Bentzon, A Panteleev, V Mitsura, E Borodulina, A Skrahina, E Denisova, S Tetradov, R Podlasin, V Riekstina, Z Kancauskiene and 12 more

Open access · greenAbstract read
In one paragraph

Article in HIV medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Uptake of the lateral flow urine LAM test in Europe and Central Asia.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 15 institutions in 8 countries.

A K BentzonCHIP (Centre of Excellence for Health, Immunity and Infections), Department of Infectious Disease, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-5438-1513
A PanteleevDepartment of HIV/TB, TB Hospital 2, St Petersburg, Russia.
V MitsuraGomel State Medical University, Gomel, Belarus.
E BorodulinaDepartment of Phthisiology and Pulmonology, Samara State Medical University of Minzdrav of Russia, Samara, Russia.
A SkrahinaRepublican Research and Practical Clinic for Pulmonology, Minsk, Belarus.
E DenisovaBotkin Hospital of Infectious Disease, St Petersburg, Russia.
S TetradovDr. Victor Babes Hospital, Bucharest, Romania.
R PodlasinWojewodski Szpital Zakanzy/Medical University of Warsaw, Warsaw, Poland.
V RiekstinaClinic of TB and Lung Diseases, Riga, Latvia.
Z KancauskieneClinic for Communicable Diseases and AIDS, Vilnius, Lithuania.
D PadutoGomel Region Clinic for Hygiene, Svetlogorsk, Belarus.
A MocroftDepartment of Infection and Population Health, University College London, London, UK.ORCID 0000-0001-8316-1122
T TrofimovaClinic for Prevention and Control of AIDS, Novgorod, Russia.
R MillerMortimer Market Clinic, London, UK.
F PostKing's College Hospital, London, UK.ORCID 0000-0002-2844-1612
A GrezesczukMedical University Teaching Hospital, Bialystok, Poland.
J D LundgrenCHIP (Centre of Excellence for Health, Immunity and Infections), Department of Infectious Disease, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
M InglotWroclaw University School of Medicine, Wroclaw, Poland.
D PodlekarevaCHIP (Centre of Excellence for Health, Immunity and Infections), Department of Infectious Disease, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
N BolokadzeInfectious Diseases, AIDS and Clinical Immunology Research Clinic, Tbilisi, Georgia.
O KirkCHIP (Centre of Excellence for Health, Immunity and Infections), Department of Infectious Disease, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-1995-1837
TB:HIV Study Group
University of Copenhagen · DKAIDS and Clinical Immunology Research Center · GEBotkin Hospital · RUGomel State Medical University · BYKing's College Hospital · GBMedical University of Warsaw · PLMortimer Market Centre · GBRegional Center for Prevention and Control of AIDS and Infectious Diseases · RURepublican Scientific and Practical Centre of Pulmonology and Tuberculosis · BYRiga East University Hospital · LVSamara State Medical University · RUSpitalul Clinic Dr. Victor Babes · ROUniversity Clinical Hospital In Bialystok · PLUniversity College London · GBUniversity of Wrocław · PL

Funding

Emory-Georgia TB Research Training ProgramD43TW007124 · FIC · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Nestani Tukvadze · 2004 to 2026
$4.6M
Department of Health RP-2016-07-012FIC NIH HHS D43 TW007124Medical Research Council MR/T001127/1
6 · The paper itself

Abstract

backgroundIn a 2013 survey, we reported distinct discrepancies in delivery of tuberculosis (TB) and HIV services in eastern Europe (EE) vs. western Europe (WE).

objectivesTo verify the differences in TB and HIV services in EE vs. WE.

methodsTwenty-three sites completed a survey in 2018 (EE, 14; WE, nine; 88% response rate). Results were compared across as well as within the two regions. When possible, results were compared with the 2013 survey.

resultsDelivery of healthcare was significantly less integrated in EE: provision of TB and HIV services at one site (36% in EE vs. 89% in WE; P = 0.034), and continued TB follow-up in one location (42% vs. 100%; P = 0.007). Although access to TB diagnostics, standard TB and HIV drugs was generally good, fewer sites in EE reported unlimited access to rifabutin/multi-drug-resistant TB (MDR-TB) drugs, HIV integrase inhibitors and opioid substitution therapy (OST). Compared with 2013, routine usage of GeneXpert was more common in EE in 2018 (54% vs. 92%; P = 0.073), as was access to moxifloxacin (46% vs. 91%; P = 0.033), linezolid (31% vs. 64%; P = 0.217), and bedaquiline (0% vs. 25%; P = 0.217). Integration of TB and HIV services (46% vs. 39%; P = 1.000) and provision of OST to patients with opioid dependency (54% vs. 46%; P = 0.695) remained unchanged.

conclusionDelivery of TB and HIV healthcare, including integration of TB and HIV care and access to MDR-TB drugs, still differs between WE and EE, as well as between individual EE sites.

Indexed as

HIV InfectionsTuberculosisAntitubercular AgentsDelivery of Health CareEuropeHumansAntitubercular Agentsclinical managementcoinfectioneastern EuropeHIVtuberculosiswestern Europe

Identifiers

PMID33215809
PMCPMC9801686
OpenAlexW3105770065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.