Evidence map›Paper›PMID 33215541›Full record

ArticleEpigenomics2021

Maternal anxiety and depression in pregnancy and DNA methylation of the

Alexandra E Dereix, Rachel Ledyard, Allyson M Redhunt, Tessa R Bloomquist, Kasey Jm Brennan, Andrea A Baccarelli, Michele R Hacker, Heather H Burris

Open access · greenAbstract read
In one paragraph

Article in Epigenomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Alexandra E DereixStritch School of Medicine, Loyola University Chicago, Chicago, IL 60153, USA.
Rachel LedyardDivision of Neonatology, Children's Hospital of Pennsylvania, Philadelphia, PA 19104, USA.
Allyson M RedhuntDepartment of Obstetrics & Gynecology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Tessa R BloomquistDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health Environmental Health Sciences, New York, NY 10032, USA.
Kasey Jm BrennanDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health Environmental Health Sciences, New York, NY 10032, USA.
Andrea A BaccarelliDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health Environmental Health Sciences, New York, NY 10032, USA.
Michele R HackerDepartment of Obstetrics & Gynecology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Heather H BurrisDivision of Neonatology, Children's Hospital of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-4510-9547
Beth Israel Deaconess Medical Center · USColumbia University · USChildren's Hospital of Philadelphia · USLoyola University Chicago · US

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
The Toxic Environment and the Epigenetics of Fetal GrowthK23ES022242 · NIEHS · CHILDREN'S HOSP OF PHILADELPHIA · PI BURRIS, HEATHER HERSON · 2013 to 2017
$790k
NCATS NIH HHS UL1 TR001102NCATS NIH HHS UL1 TR002541NIEHS NIH HHS K23 ES022242
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnxietyDepressionDNA MethylationReceptors, GlucocorticoidCpG IslandsFemaleHumansInfantPregnancyNR3C1 protein, humanReceptors, Glucocorticoidcord blooddevelopmental epigeneticsDNA methylationepigeneticsglucocorticoid receptormaternal anxietymaternal depressionNR3C1pregnancy

Identifiers

PMID33215541
PMCPMC8579934
OpenAlexW3100826817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.