Evidence map›Paper›PMID 33215008›Full record

ArticleInternational journal of ophthalmology2020

Comparison of intravitreal injection of conbercept and triamcinolone acetonide for macular edema secondary to branch retinal vein occlusion.

Miao Zhao, Ce Zhang, Xi-Mei Chen, Yan Teng, Tian-Wei Shi, Fei Liu

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Efficacy and clinical outcomes of suprachoroidal triamcinolone acetonide in diabetic macular edema patients: a single-arm systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Miao ZhaoDepartment of Ophthalmology, the Second Hospital of Dalian Medical University, Dalian 116027, Liaoning Province, China.
Ce ZhangDrug Clinical Trials Institution, the Second Hospital of Dalian Medical University, Dalian 116027, Liaoning Province, China.
Xi-Mei ChenDepartment of Ophthalmology, the Second Hospital of Dalian Medical University, Dalian 116027, Liaoning Province, China.
Yan TengDepartment of Ophthalmology, the Second Hospital of Dalian Medical University, Dalian 116027, Liaoning Province, China.
Tian-Wei ShiDepartment of Ophthalmology, the Second Hospital of Dalian Medical University, Dalian 116027, Liaoning Province, China.
Fei LiuDepartment of Ophthalmology, the Second Hospital of Dalian Medical University, Dalian 116027, Liaoning Province, China.
Second Affiliated Hospital of Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare the safety and efficacy of the intravitreal injection of conbercept (IVC) and triamcinolone acetonide (IVTA) for macular edema (ME) secondary to branch retinal vein occlusion (BRVO).

methodsA prospective, randomized clinical study. Patients with ME secondary to BRVO were randomly assigned to either IVC group or IVTA group at a ratio of 2:1 and a 12-month follow-up was performed. The efficacy outcome measures included the mean changes and differences in best corrected visual acuity (BCVA) and the central retinal thickness (CRT). The safety profiles and the mean retreatment intervals were also compared.

resultsThere was no statistically significant difference of baseline between the two groups (IVC group,

conclusionIVC could maintain or improve BCVA and reduce CRT for a longer time and have longer retreatment interval than IVTA. In addition, patients treated with IVTA are more susceptible to IOP elevation and cataract progression.

Indexed as

branch retinal vein occlusionconberceptmacular edematriamcinolone acetonide

Identifiers

PMID33215008
PMCPMC7590870
OpenAlexW3093880713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.