Evidence map›Paper›PMID 33214629›Full record

ArticleScientific reports2020

Large-scale analysis of iliopsoas muscle volumes in the UK Biobank.

Julie A Fitzpatrick, Nicolas Basty, Madeleine Cule, Yi Liu, Jimmy D Bell, E Louise Thomas, Brandon Whitcher

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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  16. Muscle group-specific skeletal muscle aging: a 5-yr longitudinal study in septuagenarians.Journal of applied physiology (Bethesda, Md. : 1985) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julie A FitzpatrickResearch Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK.
Nicolas BastyResearch Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK. n.basty@westminster.ac.uk.
Madeleine CuleCalico Life Sciences LLC, South San Francisco, CA, USA.
Yi LiuCalico Life Sciences LLC, South San Francisco, CA, USA.
Jimmy D BellResearch Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK.
E Louise ThomasResearch Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK.
Brandon WhitcherResearch Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK.

Funding

Medical Research Council MC_PC_17228Medical Research Council MC_QA137853
6 · The paper itself

Abstract

Psoas muscle measurements are frequently used as markers of sarcopenia and predictors of health. Manually measured cross-sectional areas are most commonly used, but there is a lack of consistency regarding the position of the measurement and manual annotations are not practical for large population studies. We have developed a fully automated method to measure iliopsoas muscle volume (comprised of the psoas and iliacus muscles) using a convolutional neural network. Magnetic resonance images were obtained from the UK Biobank for 5000 participants, balanced for age, gender and BMI. Ninety manual annotations were available for model training and validation. The model showed excellent performance against out-of-sample data (average dice score coefficient of 0.9046 ± 0.0058 for six-fold cross-validation). Iliopsoas muscle volumes were successfully measured in all 5000 participants. Iliopsoas volume was greater in male compared with female subjects. There was a small but significant asymmetry between left and right iliopsoas muscle volumes. We also found that iliopsoas volume was significantly related to height, BMI and age, and that there was an acceleration in muscle volume decrease in men with age. Our method provides a robust technique for measuring iliopsoas muscle volume that can be applied to large cohorts.

Indexed as

Biological Specimen BanksMagnetic Resonance ImagingAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedOrgan SizePsoas MusclesUnited Kingdom

Identifiers

PMID33214629
PMCPMC7677387

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.