Evidence map›Paper›PMID 33214593›Full record

Trial reportScientific reports2020

Efficacy of P

Paulina Sedlakova Kondelova, Alaa Mannaa, Claudine Bommer, Marwa Abdelaziz, Laurent Daeniker, Enrico di Bella, Ivo Krejci

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07664046 (A Three-arm Randomized Controlled Trial Evaluating the Effectiveness of Self- Assembling Peptide P11-4 in the Remineralization of Enamel Carious White Spot Lesions), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07664046 narecruitingnot on this mapstarted 2026, after this paper: background citation

A Three-arm Randomized Controlled Trial Evaluating the Effectiveness of Self- Assembling Peptide P11-4 in the Remineralization of Enamel Carious White Spot Lesions

TypeinterventionalSponsorMedical University of WarsawRan2026 to 2027Enrolled75ConditionsWhite Spot Lesions on Smooth Surface of ToothArmsSelf-assembling peptide P11-4, Fluoride varnish
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Advanced materials for enamel remineralization.Frontiers in bioengineering and biotechnology · 2022
    Review
  20. Self-Assembling Peptides: From Design to Biomedical Applications.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Paulina Sedlakova KondelovaUniversity of Geneva, University Dental Clinics CUMD, rue Michel-Servet 1, 1211, Geneva 4, Switzerland.
Alaa MannaaDivision of Operative Dentistry, Department of Restorative Dentistry, Faculty of Dentistry, King Abdulaziz University, P.O. Box 80209, Jeddah, 21589, Kingdom of Saudi Arabia.
Claudine BommerCredentis AG, Dorfstrasse 69, 5210, Windisch, Switzerland.
Marwa AbdelazizUniversity of Geneva, University Dental Clinics CUMD, rue Michel-Servet 1, 1211, Geneva 4, Switzerland.
Laurent DaenikerUniversity of Geneva, University Dental Clinics CUMD, rue Michel-Servet 1, 1211, Geneva 4, Switzerland.
Enrico di BellaDepartment of Political Sciences, University of Genova, P.le E. Brignole 3a, 16126, Genova, Italy.
Ivo KrejciUniversity of Geneva, University Dental Clinics CUMD, rue Michel-Servet 1, 1211, Geneva 4, Switzerland. Ivo.Krejci@unige.ch.
University of Geneva · CHCredentis (Switzerland) · CHKing Abdulaziz University · SAUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the safety and efficacy of Self-Assembling Peptide P

Indexed as

AdolescentAdultCariostatic AgentsDental CariesFemaleFluorides, TopicalHumansMaleOligopeptidesTreatment OutcomeYoung AdultCariostatic AgentsFluorides, TopicalOligopeptidesP11-4 peptide

Identifiers

PMID33214593
PMCPMC7678830
OpenAlexW3102631180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.