Evidence map›Paper›PMID 33214569›Full record

ArticleScientific reports2020

Full wave 3D inverse scattering transmission ultrasound tomography in the presence of high contrast.

James Wiskin, Bilal Malik, David Borup, Nasser Pirshafiey, John Klock

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 82 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Survey of Deep Learning and Physics-Based Approaches in Computational Wave Imaging.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2025
    Article
  5. Deep-Learning-Driven High Spatial Resolution Attenuation Imaging for Ultrasound Tomography (AI-UT).IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Full Wave Inversion and Inverse Scattering in Ultrasound Tomography/Volography.Advances in experimental medicine and biology · 2023
    Article
  13. Article
  14. 3-D Stochastic Numerical Breast Phantoms for Enabling Virtual Imaging Trials of Ultrasound Computed Tomography.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

James WiskinQT ultrasound LLC, Novato, USA. james.wiskin@qtultrasound.com.
Bilal MalikQT ultrasound LLC, Novato, USA.
David BorupQT ultrasound LLC, Novato, USA.
Nasser PirshafieyQT ultrasound LLC, Novato, USA.
John KlockQT ultrasound LLC, Novato, USA.
QT Ultrasound (United States) · US

Funding

Partnership-3: multimode quantitative ultrasound prototype breast scannerR01CA138536 · NCI · QT IMAGING, INC. · PI WISKIN, JAMES W · 2012 to 2016
$3.2M
NCI NIH HHS R01 CA138536NIH HHS NCI R01CA138536
6 · The paper itself

Abstract

We present here a quantitative ultrasound tomographic method yielding a sub-mm resolution, quantitative 3D representation of tissue characteristics in the presence of high contrast media. This result is a generalization of previous work where high impedance contrast was not present and may provide a clinically and laboratory relevant, relatively inexpensive, high resolution imaging method for imaging in the presence of bone. This allows tumor, muscle, tendon, ligament or cartilage disease monitoring for therapy and general laboratory or clinical settings. The method has proven useful in breast imaging and is generalized here to high-resolution quantitative imaging in the presence of bone. The laboratory data are acquired in ~ 12 min and the reconstruction in ~ 24 min-approximately 200 times faster than previously reported simulations in the literature. Such fast reconstructions with real data require careful calibration, adequate data redundancy from a 2D array of 2048 elements and a paraxial approximation. The imaging results show that tissue surrounding the high impedance region is artifact free and has correct speed of sound at sub-mm resolution.

Indexed as

AlgorithmsBone and BonesCancellous BoneContrast MediaFormaldehydeHumansImage Processing, Computer-AssistedImaging, Three-DimensionalKneeMagnetic Resonance ImagingTissue FixationTomographyUltrasonic WavesUltrasonographyContrast MediaFormaldehyde

Identifiers

PMID33214569
PMCPMC7677558
OpenAlexW3099387748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.