ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021
Lack of Evidence for Stereotypical Direction Columns in the Mouse Superior Colliculus.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Visual Motion Processing in The Tree Shrew Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Synergistic Geniculate and Cortical Dynamics Facilitate a Decorrelated Spatial Frequency Code in the Early Visual System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Investigating mouse superior colliculus function using two-photon calcium imaging.Frontiers in cellular neuroscience · 2026Review
- Coordination of distinct sources of excitatory inputs enhances motion selectivity in the mouse visual thalamus.Neuron · 2025Article
- A column-like organization for ocular dominance in mouse visual cortex.Nature communications · 2025Article
- Cross-modal enhancement of defensive behavior via parabigemino-collicular projections.Current biology : CB · 2024Article
- Transformation of Motion Pattern Selectivity from Retina to Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Predation without direction selectivity.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Mapping the Retina onto the Brain.Cold Spring Harbor perspectives in biology · 2024Review
- Enhancement and contextual modulation of visuospatial processing by thalamocollicular projections from ventral lateral geniculate nucleus.Nature communications · 2023Article
- Collicular circuits supporting the perceptual, motor and cognitive demands of ethological environments.Current opinion in neurobiology · 2023Review
- Stimulus edges induce orientation tuning in superior colliculus.Nature communications · 2023Article
- Article
- Retinal waves align the concentric orientation map in mouse superior colliculus to the center of vision.Science advances · 2023Article
- Article
- Panoramic visual statistics shape retina-wide organization of receptive fields.Nature neuroscience · 2023Article
- Cortical-subcortical interactions in goal-directed behavior.Physiological reviews · 2023Review
- Strong tuning for stereoscopic depth indicates orientation-specific recurrent circuitry in tree shrew V1.Current biology : CB · 2022Article
- High-density electrode recordings reveal strong and specific connections between retinal ganglion cells and midbrain neurons.Nature communications · 2022Article
- Neural mechanisms to exploit positional geometry for collision avoidance.Current biology : CB · 2022Article
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4 authors.
Funding
Abstract
Neurons in the visual system can be spatially organized according to their response properties such as receptive field location and feature selectivity. For example, the visual cortex of many mammalian species contains orientation and direction columns where neurons with similar preferences are clustered. Here, we examine whether such a columnar structure exists in the mouse superior colliculus (SC), a prominent visual center for motion processing. By performing large-scale physiological recording and two-photon calcium imaging in adult male and female mice, we show that direction-selective neurons in the mouse SC are not organized into stereotypical columns as a function of their preferred directions, although clusters of similarly tuned neurons are seen in a minority of mice. Nearby neurons can prefer similar or opposite directions in a largely position-independent manner. This finding holds true regardless of animal state (anesthetized vs awake, running vs stationary), SC depth (most superficial lamina vs deeper in the SC), research technique (calcium imaging vs electrophysiology), and stimulus type (drifting gratings vs moving dots, full field vs small patch). Together, these results challenge recent reports of region-specific organizations in the mouse SC and reveal how motion direction is represented in this important visual center.
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