Evidence map›Paper›PMID 33214282›Full record

ArticleScience (New York, N.Y.)2020

Tissue topography steers migrating

Wei Dai, Xiaoran Guo, Yuansheng Cao, James A Mondo, Joseph P Campanale, Brandon J Montell, Haley Burrous, Sebastian Streichan, Nir Gov, Wouter-Jan Rappel and 1 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Hyperactive Rac converts sublethal to lethal trogocytosis in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Hyperactive Rac converts sublethal nibbling to lethal phagocytosisbioRxiv : the preprint server for biology · 2025
    Article
  11. Collective migration modes in development, tissue repair and cancer.Nature reviews. Molecular cell biology · 2025
    Review
  12. Article
  13. Article
  14. Finishing the egg.Genetics · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wei Dai *Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA.ORCID 0000-0001-6069-9616
Xiaoran Guo *Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA.ORCID 0000-0002-3011-4514
Yuansheng CaoDepartment of Physics, University of California, San Diego, CA 92093, USA.ORCID 0000-0002-6857-6044
James A MondoDepartment of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA.ORCID 0000-0001-9703-0676
Joseph P CampanaleDepartment of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA.ORCID 0000-0003-1902-7708
Brandon J MontellIndependent researcher.
Haley BurrousDepartment of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA.ORCID 0000-0002-6440-7964
Sebastian StreichanDepartment of Physics, University of California, Santa Barbara, CA 93106, USA.
Nir GovDepartment of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0001-7774-1139
Wouter-Jan RappelDepartment of Physics, University of California, San Diego, CA 92093, USA.ORCID 0000-0003-3833-7197
Denise J MontellDepartment of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA. dmontell@ucsb.edu.ORCID 0000-0001-8924-5925

Funding

Spatiotemporal regulation of collective cell behaviors in Drosophila: Diversity Supplement for Predoctoral TrainingR01GM046425 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI MONTELL, DENISE J. · 1996 to 2025
$11.7M
Tissue flow genetics: using cartography to reveal forces driving morphogenesisR00HD088708 · NICHD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI STREICHAN, SEBASTIAN J · 2018 to 2020
$659k
Spectral Laser Scanning Biological MicroscopeS10OD010610 · OD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI RAVEN, MARY A · 2012 to 2012
$429k
NICHD NIH HHS R00 HD088708NIGMS NIH HHS R01 GM046425NIH HHS S10 OD010610
6 · The paper itself

Abstract

Moving cells can sense and respond to physical features of the microenvironment; however, in vivo, the significance of tissue topography is mostly unknown. Here, we used

Indexed as

Cell MovementAnimalsCadherinsChemotactic FactorsDrosophila melanogasterMolecular ImagingOocytesCadherinsChemotactic Factors

Identifiers

PMID33214282
PMCPMC8103818

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.