Evidence map›Paper›PMID 33213534›Full record

ArticleParasitology2021

The Kubic FLOTAC microscope (KFM): a new compact digital microscope for helminth egg counts.

Giuseppe Cringoli, Alessandra Amadesi, Maria Paola Maurelli, Biase Celano, Gabriele Piantadosi, Antonio Bosco, Lavinia Ciuca, Mario Cesarelli, Paolo Bifulco, Antonio Montresor and 1 more

Abstract read
In one paragraph

Article in Parasitology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Diagnosis of Human Trematode Infections.Advances in experimental medicine and biology · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Comparison of FECPAKParasites & vectors · 2022
    Article
  12. Parasitology · 2021
    Article
  13. Article
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Giuseppe CringoliDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, WHO Collaborating Centre ITA-116, Naples, Italy.
Alessandra AmadesiDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, WHO Collaborating Centre ITA-116, Naples, Italy.
Maria Paola MaurelliDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, WHO Collaborating Centre ITA-116, Naples, Italy.ORCID 0000-0002-7564-3356
Biase CelanoOfficina Elettronica SPA S.r.l., Naples, Italy.
Gabriele PiantadosiDepartment of Electrical Engineering and Information Technology, University of Naples Federico II, Naples, Italy.
Antonio BoscoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, WHO Collaborating Centre ITA-116, Naples, Italy.
Lavinia CiucaDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, WHO Collaborating Centre ITA-116, Naples, Italy.
Mario CesarelliDepartment of Electrical Engineering and Information Technology, University of Naples Federico II, Naples, Italy.
Paolo BifulcoDepartment of Electrical Engineering and Information Technology, University of Naples Federico II, Naples, Italy.
Antonio MontresorDepartment of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.
Laura RinaldiDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, WHO Collaborating Centre ITA-116, Naples, Italy.

Funding

World Health Organization 001
6 · The paper itself

Abstract

The Kubic FLOTAC microscope (KFM) is a compact, low-cost, versatile and portable digital microscope designed to analyse fecal specimens prepared with Mini-FLOTAC or FLOTAC, in both field and laboratory settings. In this paper, we present the characteristics of the KFM along with its first validation for fecal egg count (FEC) of gastrointestinal nematodes (GINs) in cattle. For this latter purpose, a study was performed on 30 fecal samples from cattle experimentally infected by GINs to compare the performance of Mini-FLOTAC either using a traditional optical microscope (OM) or the KFM. The results of the comparison showed a substantial agreement (concordance correlation coefficient = 0.999), with a very low discrepancy (−0.425 ± 7.370) between the two microscopes. Moreover, the KFM captured images comparable with the view provided by the traditional OM. Therefore, the combination of sensitive, accurate, precise and standardized FEC techniques, as the Mini-FLOTAC, with a reliable automated system, will permit the real-time observation and quantification of parasitic structures, thanks also to artificial intelligence software, that is under development. For these reasons, the KFM is a promising tool for an accurate and efficient FEC to improve parasite diagnosis and to assist new generations of operators in veterinary and public health.

Indexed as

AnimalsCattleCattle DiseasesFecesImaging, Three-DimensionalMicroscopyNematode InfectionsParasite Egg CountStatistics, NonparametricDigital microscopefecal egg countKubic FLOTAC microscopeMini-FLOTACTele-Parasitology

Identifiers

PMID33213534
PMCPMC7938342

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.