Evidence map›Paper›PMID 33213417›Full record

ArticleBMC infectious diseases2020

Association between renal function and co-infection with Clonorchis sinensis and Helicobacter pylori: a cross-sectional study.

Weining Xie, Yuanjun Deng, Shengxin Chen, Yifeng Wu, Ye Li, Qinhe Yang

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Weining XieDepartment of Infectious Disease, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, 528200, China.
Yuanjun DengSchool of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.
Shengxin ChenDepartment of Infectious Disease, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, 528200, China.
Yifeng WuDepartment of Infectious Disease, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, 528200, China.
Ye LiDepartment of Infectious Disease, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, 528200, China.
Qinhe YangSchool of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China. tyangqh@jnu.edu.cn.
Jinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies have shown that liver fluke infections may be associated with kidney injury and that Helicobacter pylori (Hp) may be involved in the pathogenesis of kidney diseases. However, no studies have reported the relationship between co-infection with Clonorchis sinensis (Cs) and Hp and renal function. The aim of this study was to examine the relationship between co-infection with Cs and Hp and estimated glomerular filtration rate (eGFR) in a general population, and gender-related differences were also investigated.

methodsIn the cross-sectional study, 4122 subjects from the Health Examination Center of Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine from January 2017 to December 2018 were enrolled. All participants underwent stool examination for the diagnosis of Cs infection and

resultsHp infection without Cs infection was present in 6.67% (275/4122) of subjects, while Cs infection without Hp infection was present in 33.77% (1392/4122) of subjects. Co-infection with Hp and Cs were present in 5.02% (207/4122) of subjects. Median age of the participants was 43 years (IQR 35-51). Most of the participants were male (2955/4122, 71.69%). Median eGFR was 96.61 ml/min/1.73 m

conclusionOur findings suggest that co-infection with Cs and Hp may be associated with reduced renal function in females, but not in males.

Indexed as

AdultAnimalsbeta 2-MicroglobulinBlood Urea NitrogenBreath TestsClonorchiasisClonorchis sinensisC-Reactive ProteinCross-Sectional StudiesFecesFemaleGlomerular Filtration RateHelicobacter InfectionsHelicobacter pyloriHumansKidneybeta 2-MicroglobulinC-Reactive ProteinClonorchis sinensiseGFRHelicobacter pyloriRenal function

Identifiers

PMID33213417
PMCPMC7678138
OpenAlexW3105321956

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.