ArticleBMC ophthalmology2020
Effect of biomechanical properties on myopia: a study of new corneal biomechanical parameters.
Article in BMC ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 43 citations in OpenAlex.
- Roadmap on advances in visual and physiological optics.Journal of optics (2010) · 2025Review
- The correlation between myopia severity and stress-strain index (SSI) using the Corneal Visualization Scheimpflug Technology (Corvis ST).Scientific reports · 2025Article
- Short-term digital ocular massage may weaken corneal biomechanics.Frontiers in bioengineering and biotechnology · 2025Article
- Corneal Biomechanical Characteristics and Correlation Analysis in Children With Different Refractive States.Journal of ophthalmology · 2025Article
- Exome-wide association study identifies KDELR3 mutations in extreme myopia.Nature communications · 2024Article
- Optic Nerve Head Pulsatile Displacement in Open-Angle Glaucoma after Intraocular Pressure Reduction Measured by Optical Coherence Tomography: A Pilot Study.Bioengineering (Basel, Switzerland) · 2024Article
- Refractive associations with corneal biomechanical properties among young adults: a population-based Corvis ST study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Comparative analysis of corneal parameters in simple myopic anisometropia using Scheimpflug technology.Frontiers in bioengineering and biotechnology · 2024Article
- Characterization of Corneal Biomechanics Using CORVIS ST Device in Different Grades of Myopia in a Sample of Middle Eastern Ethnicity.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Comparisons of the protein expressions between high myopia and moderate myopia on the anterior corneal stroma in human.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Refractive Associations With Whole Eye Movement Distance and Time Among Chinese University Students: A Corvis ST Study.Translational vision science & technology · 2023Article
- Analysis of the diagnostic accuracy of Belin/Ambrósio Enhanced Ectasia and Corvis ST parameters for subclinical keratoconus.International ophthalmology · 2023Article
- Comparison of two analyzer measurements focusing on material stiffness among normal, treatment-naïve, and treated glaucoma eyes.Scientific reports · 2023Article
- Changes in Stress-Strain Index in School-Aged Children: A 3-Year Longitudinal Study.Journal of ophthalmology · 2023Article
- Change in the corneal material mechanical property for small incision lenticule extraction surgery.Frontiers in bioengineering and biotechnology · 2023Article
- Effect of corneal stiffness decrease on axial length elongation in myopia determined based on a mathematical estimation model.Frontiers in bioengineering and biotechnology · 2023Article
- Effect of prostaglandin analogues on the biomechanical corneal properties in patients with open-angle glaucoma and ocular hypertension measured with dynamic scheimpflug analyzer.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Observational
- Biomechanical analysis of ocular diseases and its in vitro study methods.Biomedical engineering online · 2022Review
- A comparative and prospective study of corneal biomechanics after SMILE and FS-LASIK performed on the contralateral eyes of high myopia patients.Annals of translational medicine · 2022Article
- Unraveling the mechanobiology of cornea: From bench side to the clinic.Frontiers in bioengineering and biotechnology · 2022Review
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundTo assess the corneal stress-strain index (SSI), which is a marker for material stiffness and corneal biomechanical parameters, in myopic eyes.
methodsA total of 1054 myopic patients were included in this study. Corneal visualisation Scheimpflug technology was used to measure the SSI. Corneal biomechanics were assessed using the first and second applanation times (A1-and A2-times); maximum deflection amplitude (DefAmax); deflection area (HCDefArea); the highest concavity peak distance (HC-PD), time (HC-time), and deflection amplitude (HC-DefA); integrated radius (IR); whole eye movement (WEM); stiffness parameter (SP-A1;, biomechanically corrected intraocular pressure (BIOP); and Corvis biomechanical index (CBI). Scheimpflug tomography was used to obtain the mean keratometery (Km) and central corneal thickness (CCT). According to the spherical equivalent (SE) (low myopia: SE ≥ - 3.00D and high myopia: SE ≤ - 6.00D.), the suitable patients were divided into two groups.
resultsThe mean SSI value was 0.854 ± 0.004. The SSI had a positive correlation with A1-time ((r = 0.272), HC-time (r = 0.218), WEM (r = 0.288), SP-A1 (r = 0.316), CBI (r = 0.199), CCT (r = 0.125), bIOP (r = 0.230), and SE (r = 0.313) (all p-values<0.01). The SSI had a negative correlation with HCDefA (r = - 0.721), HCDefArea (r = - 0.665), HC-PD(r = - 0.597), IR (r = - 0.555), DefAmax (r = - 0.564), and Km (r = - 0.103) (all p-values<0.01). There were significant differences in SSI (t = 8.960, p<0.01) and IR (t = - 3.509, p<0.01) between the low and high myopia groups.
conclusionsIn different grades of myopia, the SSI values were lower in eyes with higher SEs. It indicates that the mechanical strength of the cornea may be compromised in high myopia. The SSI was positively correlated with the spherical equivalent, and it may provide a new way to study the mechanism of myopia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.