Evidence map›Paper›PMID 33213203›Full record

ArticleJournal of immunotoxicology2020

Immunotoxicity studies of trans-resveratrol in male B

Madelyn C Huang, Kimber L White, Susan A Elmore, Tai L Guo, Dori Germolec

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunotoxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Madelyn C HuangDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.ORCID 0000-0001-8286-4408
Kimber L WhiteDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA (retired).
Susan A ElmoreDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Tai L GuoDepartment of Veterinary Biosciences and Diagnostic Imaging, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Dori GermolecDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
National Institute of Environmental Health Sciences · USUniversity of Georgia · USVirginia Commonwealth University · US

Funding

Toxicological Assessments for the National Toxicology ProgramZIAES103316 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WALKER, NIGEL J · 2016 to 2019
$31.9M
Toxicologic Pathology Evaluations for the National Toxicology ProgramZIAES103319 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI MALARKEY, DAVID · 2016 to 2019
$25.2M
Toxicological Assessments for the Division of the National Toxicology ProgramZICES103316 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WALKER, NIGEL J · 2020 to 2021
$18.5M
Toxicologic Pathology Evaluations for the Division of the National Toxicology ProgramZICES103319 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI CESTA, MARK · 2020 to 2021
$12.3M
CHEMISTRY SUPPORT SERVICES FOR THE ENVIRONMENTAL TPN01ES005455 · NIEHS · RESEARCH TRIANGLE INSTITUTE · PI SPARACINO, CHARLES · 2000 to 2000
$3.6M
Intramural NIH HHS Z99 ES999999Intramural NIH HHS ZIA ES103316Intramural NIH HHS ZIA ES103319NIEHS NIH HHS N01 ES005455NIEHS NIH HHS N01 ES055538
6 · The paper itself

Abstract

Resveratrol is a naturally occurring polyphenol that is being investigated to treat and prevent various diseases, both experimentally and in the clinic. Despite increased use and interest in resveratrol due to its immunomodulatory properties, there is a lack of studies evaluating potential toxicities, particularly immunotoxicity, associated with resveratrol use. A previous 2-week study found decreasing thymus weight in male B

Indexed as

Administration, OralAnimalsDietary SupplementsDrug-Related Side Effects and Adverse ReactionsImmune SystemImmunity, CellularImmunity, HumoralImmunity, InnateImmunologic FactorsMaleMiceMice, Inbred C3HMice, Inbred C57BLResveratrolThymus GlandImmunologic FactorsResveratroldietary supplementimmunotoxicityinflammationmiceResveratrol

Identifiers

PMID33213203
PMCPMC7961840
OpenAlexW3104417936

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.