Evidence map›Paper›PMID 33213091›Full record

ReviewCells2020

The Role of Histone Variants in the Epithelial-To-Mesenchymal Transition.

Imtiaz Nisar Lone, Burcu Sengez, Ali Hamiche, Stefan Dimitrov, Hani Alotaibi

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Imtiaz Nisar LoneIzmir Biomedicine and Genome Center, Izmir 35340, Turkey.
Burcu SengezIzmir Biomedicine and Genome Center, Izmir 35340, Turkey.ORCID 0000-0002-1833-4135
Ali HamicheInstitute of Genetics and Molecular and Cellular Biology (IGBMC), 1 rue Laurent Fries, 67400 Illkirch, France.
Stefan DimitrovIzmir Biomedicine and Genome Center, Izmir 35340, Turkey.
Hani AlotaibiIzmir Biomedicine and Genome Center, Izmir 35340, Turkey.ORCID 0000-0001-7423-9653
Izmir University · TRCentre National de la Recherche Scientifique · FRInstitut de génétique et de biologie moléculaire et cellulaire · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epithelial-to-mesenchymal transition (EMT) is a physiological process activated during early embryogenesis, which continues to shape tissues and organs later on. It is also hijacked by tumor cells during metastasis. The regulation of EMT has been the focus of many research groups culminating in the last few years and resulting in an elaborate transcriptional network buildup. However, the implication of epigenetic factors in the control of EMT is still in its infancy. Recent discoveries pointed out that histone variants, which are key epigenetic players, appear to be involved in EMT control. This review summarizes the available data on histone variants' function in EMT that would contribute to a better understanding of EMT itself and EMT-related diseases.

Indexed as

Epigenesis, GeneticEpithelial-Mesenchymal TransitionGenetic VariationHistonesHumansHistoneschromatinepigeneticsepithelial-to-mesenchymal transitionhistone variantsnucleosomes

Identifiers

PMID33213091
PMCPMC7698467
OpenAlexW3103740489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.