Evidence map›Paper›PMID 33213088›Full record

ArticleCells2020

Proteomic Insights into Senescence of Testicular Peritubular Cells from a Nonhuman Primate Model.

Jan B Stöckl, Nina Schmid, Florian Flenkenthaler, Charis Drummer, Rüdiger Behr, Artur Mayerhofer, Georg J Arnold, Thomas Fröhlich

Abstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. June in focus in HCB: advanced methodologies.Histochemistry and cell biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Cannabidiol-induced transcriptomic changes and cellular senescence in human Sertoli cells.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Article
  7. Article
  8. Review
  9. Testicular aging, male fertility and beyond.Frontiers in endocrinology · 2022
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jan B StöcklLaboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU München, 81377 Munich, Germany.ORCID 0000-0002-6432-1271
Nina SchmidLMU München, Biomedical Center (BMC), Anatomy III-Cell Biology, 82152 Martinsried, Germany.
Florian FlenkenthalerLaboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU München, 81377 Munich, Germany.
Charis DrummerPlatform Degenerative Diseases, German Primate Center, Leibniz Institute for Primate Research, 37077 Göttingen, Germany.
Rüdiger BehrPlatform Degenerative Diseases, German Primate Center, Leibniz Institute for Primate Research, 37077 Göttingen, Germany.ORCID 0000-0001-8816-6619
Artur MayerhoferLMU München, Biomedical Center (BMC), Anatomy III-Cell Biology, 82152 Martinsried, Germany.ORCID 0000-0002-9388-4639
Georg J ArnoldLaboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU München, 81377 Munich, Germany.
Thomas FröhlichLaboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU München, 81377 Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related changes in the human testis may include morphological alterations, disturbed steroidogenesis, and impaired spermatogenesis. However, the specific impact of cell age remains poorly understood and difficult to assess. Testicular peritubular cells fulfill essential functions, including sperm transport, contributions to the spermatogonial stem cell niche, and paracrine interactions within the testis. To study their role in age-associated decline of testicular functions, we performed comprehensive proteome and secretome analyses of repeatedly passaged peritubular cells from

Indexed as

AgingAnimalsCallithrixCells, CulturedCellular SenescenceDisease Models, AnimalMaleProteomicsTestisagingcellular modelmarmoset monkeynonhuman primateproteomesecretomesenescencetestis

Identifiers

PMID33213088
PMCPMC7698562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.