Evidence map›Paper›PMID 33213001›Full record

ReviewMolecules (Basel, Switzerland)2020

Development of Fish Immunity and the Role of β-Glucan in Immune Responses.

Marianna V Rodrigues, Fábio S Zanuzzo, João Fernando A Koch, Carlos Alberto F de Oliveira, Petr Sima, Vaclav Vetvicka

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 110 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Vitamin DApplied microbiology and biotechnology · 2026
    Review
  6. Article
  7. Article
  8. Dietary American Cockroach (Aquaculture nutrition · 2026
    Article
  9. Review
  10. Production of β-Glucans byInternational journal of molecular sciences · 2025
    Review
  11. Article
  12. Article
  13. Aquaculture nutrition · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Marianna V RodriguesBiotechnology Institute, UNESP-São Paulo State University (Unesp), Alameda das Tecomarias s/n, 18607-440 Botucatu, São Paulo, Brazil.ORCID 0000-0001-6148-1969
Fábio S ZanuzzoDepartment of Ocean Sciences, Memorial University, St. John's, NL A1C5S7, Canada.ORCID 0000-0001-9854-8696
João Fernando A KochDepartment of Research and Development, Biorigin Company, Fazenda São José s/n, 17290-000 Macatuba, São Paulo, Brazil.
Carlos Alberto F de OliveiraDepartment of Research and Development, Biorigin Company, Fazenda São José s/n, 17290-000 Macatuba, São Paulo, Brazil.
Petr SimaInstitute of Microbiology, Czech Academy of Sciences, 14220 Prague, Czech Republic.
Vaclav VetvickaDepartment of Pathology, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0002-3227-2938
Czech Academy of Sciences · CZMemorial University of Newfoundland · CAUniversidade Estadual Paulista (Unesp) · BRUniversity of Louisville · US

Funding

Institutional grant (CZ) RVO 61388971
6 · The paper itself

Abstract

Administration of β-glucans through various routes, including immersion, dietary inclusion, or injection, have been found to stimulate various facets of immune responses, such as resistance to infections and resistance to environmental stress. β-Glucans used as an immunomodulatory food supplement have been found beneficial in eliciting immunity in commercial aquaculture. Despite extensive research involving more than 3000 published studies, knowledge of the receptors involved in recognition of β-glucans, their downstream signaling, and overall mechanisms of action is still lacking. The aim of this review is to summarize and discuss what is currently known about of the use of β-glucans in fish.

Indexed as

Immunity, InnateAnimalsAquaculturebeta-GlucansDietFishesImmunologic Factorsbeta-GlucansImmunologic Factorsfeedingfishglucanhealthimmunityinfection

Identifiers

PMID33213001
PMCPMC7698520
OpenAlexW3104468022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.