Evidence map›Paper›PMID 33212933›Full record

ArticleNutrients2020

Circulatory and Urinary B-Vitamin Responses to Multivitamin Supplement Ingestion Differ between Older and Younger Adults.

Pankaja Sharma, Soo Min Han, Nicola Gillies, Eric B Thorstensen, Michael Goy, Matthew P G Barnett, Nicole C Roy, David Cameron-Smith, Amber M Milan

Open access · goldAbstract readComparative Study
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Scientific opinion on the tolerable upper intake level for vitamin B6.EFSA journal. European Food Safety Authority · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Pankaja SharmaThe Liggins Institute, University of Auckland, Auckland 1023, New Zealand.ORCID 0000-0002-8213-8585
Soo Min HanThe Liggins Institute, University of Auckland, Auckland 1023, New Zealand.ORCID 0000-0002-5354-6184
Nicola GilliesThe Liggins Institute, University of Auckland, Auckland 1023, New Zealand.
Eric B ThorstensenThe Liggins Institute, University of Auckland, Auckland 1023, New Zealand.
Michael GoyThe Liggins Institute, University of Auckland, Auckland 1023, New Zealand.
Matthew P G BarnettRiddet Institute, Palmerston North 4474, New Zealand.ORCID 0000-0002-5186-5579
Nicole C RoyRiddet Institute, Palmerston North 4474, New Zealand.ORCID 0000-0002-6744-9705
David Cameron-SmithThe Liggins Institute, University of Auckland, Auckland 1023, New Zealand.ORCID 0000-0002-0144-5816
Amber M MilanThe Liggins Institute, University of Auckland, Auckland 1023, New Zealand.ORCID 0000-0002-9559-7326
University of Auckland · NZAgResearch · NZAgency for Science, Technology and Research · SG

Funding

AgResearch A21246Maurice and Phyllis Paykel Trust 3716230University of Auckland 3716936
6 · The paper itself

Abstract

Multivitamin and mineral (MVM) supplements are frequently used amongst older populations to improve adequacy of micronutrients, including B-vitamins, but evidence for improved health outcomes are limited and deficiencies remain prevalent. Although this may indicate poor efficacy of supplements, this could also suggest the possibility for altered B-vitamin bioavailability and metabolism in older people. This open-label, single-arm acute parallel study, conducted at the Liggins Institute Clinical Research Unit in Auckland, compared circulatory and urinary B-vitamer responses to MVM supplementation in older (70.1 ± 2.7 y,

Indexed as

AgingBreakfastPostprandial PeriodAdultAgedDiet RecordsEnergy IntakeFemaleHumansMaleNutrientsVitamin B ComplexYoung AdultNutrientsVitamin B ComplexageingB-vitamin bioavailabilityB-vitamins supplementexcretionultra-high performance liquid chromatography coupled with mass spectrometryvitamin B6

Identifiers

PMID33212933
PMCPMC7698360
OpenAlexW3105487294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.