ArticleChildren (Basel, Switzerland)2020
Febrile Seizures and Respiratory Viruses Determined by Multiplex Polymerase Chain Reaction Test and Clinical Diagnosis.
Article in Children (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- The baseline risk of multiple febrile seizures in the same febrile illness: a meta-analysis.European journal of pediatrics · 2022Pooled it
- Association of respiratory viral detection with complex febrile seizures and hospitalisation in children after the COVID-19 pandemic: a retrospective observational study.BMJ paediatrics open · 2026Observational
- Impact of the Omicron Strain on Febrile Convulsions Requiring Hospitalization in Children: A Single-Center Observational Study.Pediatric reports · 2024Article
- Comparison of clinical characteristics and disease burden of febrile seizures in children with and without COVID-19.BMC pediatrics · 2024Article
- Clinical comparison of HMPV and RSV infections in hospitalised Malaysian children: A propensity score matched study.The clinical respiratory journal · 2024Observational
- Evaluation of patients presenting with febrile seizures in an Iranian referral hospital: emphasis on the frequency of meningitis and co-infections.BMC pediatrics · 2023Article
- Characteristics of febrile seizures with SARS-CoV-2 infection in the Omicron era.Translational pediatrics · 2023Article
- Pathogenetic and etiologic considerations of febrile seizures.Clinical and experimental pediatrics · 2023Article
- Clinical features of febrile seizures in children with COVID-19: an observational study from a tertiary care hospital in China.Frontiers in pediatrics · 2023Article
- Impact of the COVID-19 Pandemic on Diagnostic Frequency of Febrile Seizures: An Electronic Health Record Database Observational Study.The Neurohospitalist · 2023Article
- Febrile seizure in children with COVID-19 during the Omicron wave.Frontiers in pediatrics · 2023Article
- Seasonal epidemiological and clinical characteristics of pediatric patients with human parainfluenza virus infection by serotype: a retrospective study.Virology journal · 2022Article
- Evaluation of Febrile Seizure Diagnoses Associated With COVID-19.Journal of child neurology · 2022Article
- General Characteristics of Children with Single- and Co-Infections and Febrile Seizures with a Main Focus on Respiratory Pathogens: Preliminary Results.Pathogens (Basel, Switzerland) · 2021Article
- Seizures Related to Influenza in Pediatric Patients: A Comparison with Seizures Associated with Other Respiratory Viral Infections.Journal of clinical medicine · 2021Article
- [A clinical study of influenza A virus infection with neurological symptoms in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Febrile seizure (FS) is a common benign seizure disorder of young children. Although upper respiratory tract infection is the cause of fever in most episodes of FS, studies to identify respiratory viruses using a multiplex polymerase chain reaction (mPCR) test have rarely been performed for children with FS. Medical records of children presenting with FS between January 2015 and December 2019 were retrospectively reviewed. Respiratory viruses identified by a rapid influenza detection test and mPCR test were investigated, and their seasonal distribution and the association between viral identification and seizure characteristics were determined. A total of 607 episodes of FS were analyzed: 81.1% of cases were generalized tonic-clonic seizures, 81.5% occurred within 24 h after fever onset, and 87.3% continued for ≤5 min. Complex FS occurred in 17.5% of FS episodes, and epilepsy was diagnosed in 2.5% of tracked cases. Of the 138 mPCR tests performed in 235 hospitalized episodes of FS, 112 (81.2%) tested positive for respiratory viruses: rhinovirus, enterovirus, adenovirus, and influenza virus were most frequently identified. The identified respiratory viruses showed similar seasonal distributions as were observed in community-acquired respiratory tract infections. The identification of a specific respiratory virus was not significantly associated with seizure characteristics or the development of complex FS. In conclusion, respiratory viruses, showing similar seasonal distributions with community-acquired respiratory tract infections and no significant association with the severity and outcomes of FS, should not be rigorously tested for in children with FS.
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