Evidence map›Paper›PMID 33212911›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Next-Generation Sequencing in Tumor Diagnosis and Treatment.

Dario de Biase, Matteo Fassan, Umberto Malapelle

Registry-linked trialAbstract readEditorial
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06929910 (Evaluation of Systemic Therapy and the Effectiveness of Circulating Tumor DNA), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06929910 recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of Systemic Therapy and the Effectiveness of Circulating Tumor DNA (ctDNA) Assays in Monitoring Treatment Response in Patients With Metastatic Cancer Undergoing K4Care Testing

Typeobservational_patient_registrySponsorGene SolutionsRan2025 to 2027Enrolled200ConditionsMetastatic Cancers
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Pathologica · 2023
    Review
  3. Review
  4. Next generation sequencing in cytology.Cytopathology : official journal of the British Society for Clinical Cytology · 2021
    Review
  5. Molecular alterations in pancreatic tumors.World journal of gastroenterology · 2021
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dario de BiaseDepartment of Pharmacy and Biotechnology (FaBiT), Molecular Pathology Laboratory, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-0609-8817
Matteo FassanDepartment of Medicine (DIMED), Surgical Pathology Unit, University of Padua, 35121 Padua, Italy.ORCID 0000-0001-6515-5482
Umberto MalapelleDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-3211-9957

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Next-Generation Sequencing (NGS) allows for the sequencing of multiple genes at a very high depth of coverage [...].

Identifiers

PMID33212911
PMCPMC7698429

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.