ArticleMetabolites2020
Blood Metabolomic Profiling Confirms and Identifies Biomarkers of Food Intake.
Article in Metabolites, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Multi-omics analysis of associations between host demographics and saliva metabolome, sugar profiles, and microbiome profiles.Scientific reports · 2026Article
- Elemental and biomolecular changes in serum as indicators of SPION action in the body: analysis using TXRF, FTIR and Raman spectroscopy.Scientific reports · 2025Article
- Article
- Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Effects of diets on risks of cancer and the mediating role of metabolites.Nature communications · 2024Article
- Cohort profile update-overview of over 35 years of research in the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study.European journal of nutrition · 2024Review
- Exploring Human Metabolome after Wine Intake-A Review.Molecules (Basel, Switzerland) · 2023Review
- Article
- Identification of plasma metabolites associated with modifiable risk factors and endophenotypes reflecting Alzheimer's disease pathology.European journal of epidemiology · 2023Article
- Human Archaeological Dentin as Source of Polar and Less Polar Metabolites for Untargeted Metabolomic Research: The Case ofMetabolites · 2023Article
- PPI-Induced Changes in Plasma Metabolite Levels Influence Total Hip Bone Mineral Density in a UK Cohort.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023Article
- Untargeted Metabolome Analysis of Alcohol-Exposed Pregnancies Reveals Metabolite Differences That Are Associated with Infant Birth Outcomes.Nutrients · 2022Article
- Identification of Single and Combined Serum Metabolites Associated with Food Intake.Metabolites · 2022Article
- Dynamic patterns of postprandial metabolic responses to three dietary challenges.Frontiers in nutrition · 2022Article
- Mass Spectrometry-Based Flavor Monitoring of Peruvian Chocolate Fabrication Process.Metabolites · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Metabolomics can be a tool to identify dietary biomarkers. However, reported food-metabolite associations have been inconsistent, and there is a need to explore further associations. Our aims were to confirm previously reported food-metabolite associations and to identify novel food-metabolite associations. We conducted a cross-sectional analysis of data from 849 participants (57% men) of the PopGen cohort. Dietary intake was obtained using FFQ and serum metabolites were profiled by an untargeted metabolomics approach. We conducted a systematic literature search to identify previously reported food-metabolite associations and analyzed these associations using linear regression. To identify potential novel food-metabolite associations, datasets were split into training and test datasets and linear regression models were fitted to the training datasets. Significant food-metabolite associations were evaluated in the test datasets. Models were adjusted for covariates. In the literature, we identified 82 food-metabolite associations. Of these, 44 associations were testable in our data and confirmed associations of coffee with 12 metabolites, of fish with five, of chocolate with two, of alcohol with four, and of butter, poultry and wine with one metabolite each. We did not identify novel food-metabolite associations; however, some associations were sex-specific. Potential use of some metabolites as biomarkers should consider sex differences in metabolism.
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