Evidence map›Paper›PMID 33212421›Full record

ReviewPhysica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)2020

Update on latest advances in time-of-flight PET.

Suleman Surti, Joel S Karp

Abstract readReview
In one paragraph

Review in Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Performance Evaluation of SmartBrain: A Wearable PET System for Human Brain Imaging.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
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  5. Article
  6. Timing Performance with Broadcom Metal Trench Silicon Photomultipliers.IEEE transactions on radiation and plasma medical sciences · 2025
    Article
  7. FPGA-based digitizer for BGO-based time-of-flight PET.Physics in medicine and biology · 2025
    Article
  8. Artificial intelligence for response prediction and personalisation in radiation oncology.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Review
  9. Development of Whole-Body TOF-DOI PET Detector Using Dual-Ended Readout Method.IEEE transactions on instrumentation and measurement · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Radiation Detectors and Sensors in Medical Imaging.Sensors (Basel, Switzerland) · 2024
    Review
  14. Review
  15. Role ofCancers · 2024
    Review
  16. Article
  17. Article
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  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Suleman SurtiDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: surti@pennmedicine.upenn.edu.
Joel S KarpDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: joelkarp@pennmedicine.upenn.edu.

Funding

Time-of-Flight PET for Improved Whole-Body ImagingR01CA113941 · NCI · UNIVERSITY OF PENNSYLVANIA · PI JOEL S KARP, Suleman Surti · 2006 to 2026
$9.8M
High Performance, Quantitative Breast PET Scanner Integrated With TomosynthesisR01CA196528 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ANDREW DOUGLAS ARNOLD MAIDMENT, Suleman Surti · 2016 to 2026
$5.9M
Optimization of Clinical and Research PET ImagingR01EB028764 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI SURTI, SULEMAN · 2020 to 2023
$2.2M
Energy-Based Scatter Estimation Algorithm for Accurate Quantitative PET ImagingR21CA239177 · NCI · UNIVERSITY OF PENNSYLVANIA · PI SURTI, SULEMAN · 2019 to 2020
$370k
NCI NIH HHS R01 CA113941NCI NIH HHS R01 CA196528NCI NIH HHS R21 CA239177NIBIB NIH HHS R01 EB028764
6 · The paper itself

Abstract

This paper provides an update on time-of-flight (TOF) PET with a focus on latest hardware developments leading to current commercial PET/CT instruments. We describe advances in scintillator development, new photosensors and associated electronics readout, and detector designs for utilization in complete systems. Next, we introduce the latest commercial PET/CT scanners based on the aforementioned technologies, and discuss the detector design choices made that are relevant to differences in the system performance. Finally, we end with a discussion of the latest performance benchmarks for improved timing in PET detectors, challenges in scaling this performance to a complete system, and the outlook towards achieving a sub-50 ps coincidence timing resolution (CTR) in a PET detector.

Indexed as

Positron-Emission TomographyPositron Emission Tomography Computed TomographyElectronicsCoincidence timing resolutionScintillatorSiPMTime-of-flight PET

Identifiers

PMID33212421
PMCPMC7749844

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.